Digital Social Hour

Alzheimer’s Starts Decades Before Symptoms... | David Perlmutter | DSH #1888

March 26, 2026·30 min·6-min readinterviewhealth
Podzilla Summary (6 min)
TLDR
Brain health is determined decades before cognitive symptoms appear, and metabolic health — particularly blood sugar and insulin regulation — is the primary driver of whether the brain's immune cells protect or destroy neural tissue. The key to preventing Alzheimer's lies not in genetics

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Guest

D

David Perlmutter

interview on Digital Social Hour

Mentions

Books, people, and resources mentioned in this episode.

People

David PerlmutterSean KellySarah Gottfried

Books

Brain Defendersby David Perlmutter

Companies

Function Health

Research & Papers

Neijing

Topics

BiohackingGut HealthLongevityMental HealthNeuroscienceNutritionSleep

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