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Proactive - Interviews for investors: Daily Summaries Delivered
by Proactive
Welcome to the Proactive podcast channel – the destination for breaking news on growth companies and up to the minute market coverage. Here we plug you into what’s new and exciting in the world of business.
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- Yesterday4 min
Medicus advances Teverelix development with EU Phase 2b trial submission in Prostate Cancer
Medicus Pharma Chief Medical Officer Dr Faisal Mehmud joined Steve Darling from Proactive to discuss the company’s successful submission of a substantial modification application through the European Union Clinical Trials Information System (CTIS), supporting the planned Phase 2b study of Teverelix® in advanced prostate cancer. Mehmud said the submission marks an important step in advancing Teverelix® toward registrational development, with a particular focus on prostate cancer patients who have elevated cardiovascular risk and require androgen deprivation therapy (ADT). This patient population represents a significant unmet medical need, as cardiovascular complications remain a major consideration in treatment selection and long-term management. The planned Phase 2b study is designed to optimize dose selection and further evaluate the pharmacokinetic, pharmacodynamic, efficacy, and safety profile of Teverelix® ahead of later-stage development. The data generated will help guide future registrational studies and support regulatory discussions in both Europe and the United States. Medicus has already engaged extensively with the U.S. Food and Drug Administration regarding its advanced prostate cancer development strategy, including future clinical programs focused on patients with heightened cardiovascular risk. Subject to regulatory review and approval, the company expects to begin patient enrollment later this year. Results from the study are anticipated to play a key role in determining optimal dosing, refining pivotal trial design, and advancing interactions with global regulatory agencies. Management’s objective is to position Teverelix® as a best-in-class hormonal therapy specifically developed for advanced prostate cancer patients where cardiovascular safety is a critical treatment consideration. #proactiveinvestors #nasdaq #mdcx #tsxv #mdcx #pharma #ClinicalTrials #Phase2 #Teverelix #Biotech #DrugDevelopment #FDA #Urology #BPH #AUR #MensHealth #PharmaInnovation #Healthcare #MedicalResearch #Biopharma
- Yesterday5 min
Standard Uranium intersects radioactivity at Davidson River as summer drill program advances
Standard Uranium Vice President of Exploration Sean Hillacre joined Steve Darling from Proactive to provide an update on the company’s ongoing summer drill program at its flagship Davidson River Project in Saskatchewan’s Athabasca Basin. Drilling commenced on June 1, with approximately 900 metres completed to date across two active drill holes targeting the Bronco and Thunderbird corridors. The first hole of the campaign, DR-26-040, intersected a total of three metres of anomalous radioactivity exceeding 300 counts per second (cps), including peak readings of 540, 780, and 1,650 cps between 464 and 466 metres depth. Hillacre noted that both drill holes have encountered strongly graphitic basement structures accompanied by significant hydrothermal alteration, including hematite and clay, geological features commonly associated with uranium mineralization in the Athabasca Basin. The anomalous radioactivity identified in DR-26-040 is linked to brittle reactivated structures along the Bronco corridor, further supporting the company’s exploration model. The summer program is scheduled to continue through August 2026 and is focused on discovering basement-hosted high-grade uranium mineralization along the same regional structural trends that host major deposits such as NexGen Energy’s Arrow deposit and Paladin Energy’s Triple R deposit. Standard Uranium has integrated ExoSphere multiphysics data with historical drilling results, gravity surveys, electromagnetic conductors, and machine-learning targeting to refine its exploration strategy. Management believes this highly integrated approach has significantly enhanced its understanding of the subsurface geology across the project’s 30,737-hectare land package. With two drill rigs operating around the clock, the company is accelerating testing of what it describes as its highest-confidence targets generated to date at Davidson River. Management believes the combination of favorable geology, anomalous radioactivity, advanced geophysical targeting, and strategic location within a prolific uranium district supports the project's significant discovery potential. #proactiveinvestors #standarduraniumltd #tsxv #stnd #otcqb #sttdf #mining #uranium #DavidsonRiver #UraniumExploration #AthabascaBasin #HighGradeUranium #CriticalMinerals #DrillingProgram #Geophysics #MachineLearning #ALS_GoldSpot #ExplorationUpdate #SaskatchewanMining #ResourceDiscovery #NuclearEnergy
- Yesterday7 min
Medicus advances Teverelix and SkinJect programs with key regulatory filings
Medicus Pharma CEO Dr Raza Bokhari joined Steve Darling from Proactive to discuss two significant regulatory milestones that advance the company’s pipeline in women’s health and rare disease oncology. The company has submitted an Investigational New Drug (IND) application to the Department of Health – Abu Dhabi for PRECISION-E2, a first-of-its-kind Phase 2a genomics-enabled clinical trial evaluating Teverelix® in women with symptomatic endometriosis. The randomized, placebo-controlled study is expected to enroll approximately 84 women across multiple sites in the UAE and will leverage participants from the Emirati Genome Program, one of the world’s largest national genomics initiatives. The trial is designed to combine clinical outcomes, hormonal biomarkers, pharmacokinetic and pharmacodynamic data, and genomic analysis to better understand treatment response variability. Researchers will evaluate three Teverelix treatment regimens with the goal of identifying the optimal dose and administration method while achieving controlled estradiol suppression within the therapeutic “Barbieri Window” and minimizing side effects such as hot flashes and bone loss. In a separate development, Medicus announced the submission of a Rare Pediatric Disease Designation (RPDD) request to the U.S. Food and Drug Administration for SkinJect®, its investigational doxorubicin-containing microneedle array patch, for the treatment of basal cell carcinoma in patients with Gorlin Syndrome, a rare inherited disorder associated with recurrent skin cancers. The RPDD application follows the company’s previously submitted Orphan Drug Designation request and its planned registrational study design, both of which remain under FDA review. Medicus said the development strategy for Gorlin Syndrome has been shaped through consultations with clinical experts and the Gorlin Syndrome Alliance patient advocacy organization. Management believes these regulatory filings represent important steps toward advancing precision medicine approaches in both endometriosis and rare skin cancer treatment, while potentially creating new therapeutic options for patients with significant unmet medical needs. #proactiveinvestors #nasdaq #mdcx #tsxv #mdcx #pharma #Teverelix #Endometriosis #PrecisionMedicine #Endometriosis #GorlinSyndrome #PrecisionMedicine #Biotech #ClinicalTrials #RareDisease #DrugDevelopment
- Yesterday7 min
Trillion Energy highlights strategic location advantage at M47 oil project in Türkiye
Trillion Energy Vice President and Deputy General Manager Tolga Terzi joined Steve Darling from Proactive to discuss the importance of “closeology” and how proximity to existing oil production supports the company’s M47 oil block development project in southeastern Türkiye. Terzi explained that in the oil and gas industry, being located near producing fields can significantly reduce exploration risk by providing valuable information about geology, reservoir characteristics, infrastructure, and development requirements before drilling begins. The M47 block is situated in one of Türkiye’s most active oil-producing regions, approximately 57 kilometres from the Syrian border and 90 to 100 kilometres from the Iraqi border. The acreage lies near several producing fields operated by Turkish Petroleum Corporation (TPAO), including the Sehit Ayabuke Yalcin and Sehit Esma Cevik fields. According to Terzi, TPAO has made multiple discoveries in the area in recent years and has steadily expanded drilling activity closer to Trillion’s acreage. In 2025, Trillion and its partners drilled two wells and encountered oil within the same carbonate Cretaceous reservoirs that host production in nearby fields. “We have drilled this. We have two wells in 2025 with our partners, and we encountered the same quality of oil in the same carbonate Cretaceous reservoirs,” Terzi said. He also noted that existing infrastructure, including a recently completed regional pipeline and access to major oilfield service providers, could support future development activities and potentially reduce project execution risks. Management believes the project benefits from being located adjacent to established production rather than being a purely conceptual exploration target, providing important geological validation and development advantages as the company advances the M47 project. #proactiveinvestors #trillionenergyinternational #cse #tcf #otcqb #trlef #OilDiscovery #TurkeyEnergy #OilAndGas #TurkeyEnergy #EnergyExploration #OilProduction #EnergySector #MiddleEastEnergy #ResourceDevelopment #EnergyInfrastructure #OilDiscovery #closeology
- Yesterday5 min
Abacus launches AI-Powered LifeARC platform following strategic investment in Manning & Napier
Abacus Global Management CEO Jay Jackson joined Steve Darling from Proactive to discuss the launch of LifeARC™, the company’s proprietary AI-powered lifespan modeling platform, and how it is being integrated into its broader wealth management strategy. Jackson explained that LifeARC™ leverages more than 20 years of proprietary data collected by Abacus to create personalized lifespan projections based on an individual’s medical history, health conditions, medications, genetics, and biometrics. Unlike traditional actuarial tables or population-based estimates, the platform continuously updates as a person's health profile changes, providing a dynamic model of expected longevity. The personalized lifespan model is designed to help improve financial planning by answering critical questions around retirement income, portfolio sustainability, healthcare costs, wealth preservation, and legacy planning. According to Jackson, understanding not just how much wealth a client has, but how long that wealth may need to last, can significantly improve financial decision-making. The discussion also highlighted Abacus’s recent investment of more than $50 million in wealth management firm Manning & Napier, which manages approximately $18 billion in assets and serves more than 3,400 clients. Jackson said the investment was driven by a strategic objective to bring LifeARC™ directly into client portfolios and financial planning conversations. By partnering with an established advisory platform, Abacus believes it can accelerate adoption of its technology while providing advisors with a unique tool that differentiates their services. Jackson noted that while many firms focus on projecting investment returns, LifeARC™ adds a new dimension by helping advisors estimate how long client assets may need to support retirement and future healthcare needs. The Manning & Napier partnership represents the first step in a broader strategy to expand LifeARC™ across the wealth management industry. Jackson indicated that discussions with other advisory firms are already underway as Abacus looks to establish lifespan-based financial planning as a new standard within the sector. Management believes the combination of artificial intelligence, proprietary health data, and financial planning expertise creates a powerful competitive advantage and positions LifeARC™ as a transformative tool for retirement and wealth management planning. #proactiveinvestors #abacusglobalmanagement #nasdaq #abl #EarningsBeat #FinancialGrowth #LifeSettlements #LifeARC #ArtificialIntelligence #WealthManagement #FinancialPlanning #Fintech #RetirementPlanning #AIFinance #ManningAndNapier #WealthTech
- Yesterday8 min
Lloyd Capital sees opportunity in high-quality businesses as market volatility creates value
Cedric Jacque, Partner, Investment Manager Lloyd Capital joined Steve Darling from Proactive to discuss the firm’s Focus Equity Portfolio strategy, its disciplined value-investing philosophy, and where it is finding attractive opportunities in today’s market environment. Speaking from Zurich, Jacque explained that Lloyd Capital manages approximately $2 billion in assets and focuses on investing in publicly traded companies with strong fundamentals, sustainable competitive advantages, attractive profitability, and compelling valuations. The firm’s Focus Equity Portfolio is intentionally concentrated, with roughly 80% of assets invested in just 20 holdings, reflecting a high-conviction approach to stock selection. Jacque emphasized that Lloyd Capital views stocks as ownership interests in businesses rather than short-term trading vehicles. The firm’s investment philosophy centers on identifying companies capable of generating substantial free cash flow over time relative to the price paid for their shares. As Jacque noted, “You buy a stock of a company that will deliver you over time an amount of free cash that is much higher than what you pay for.” The discussion highlighted Lloyd Capital’s extensive research process, which includes evaluating competitive advantages, pricing power, management quality, capital allocation decisions, corporate culture, and customer relationships. The firm also conducts field visits and engages directly with company management teams and stakeholders to gain deeper insights into business performance and long-term prospects. Among current investment opportunities, Jacque pointed to Chinese hotel operator H World and Canadian software leader Constellation Software. He noted that concerns surrounding artificial intelligence and its potential impact on software companies have created valuation opportunities in selected businesses that Lloyd Capital believes remain well-positioned for long-term growth. According to Jacque, market volatility and shifting investor sentiment can often create attractive entry points into high-quality companies, allowing disciplined investors to acquire strong businesses at more favorable prices. With a long-term investment horizon and a focus on business fundamentals, Lloyd Capital continues to seek opportunities where market prices diverge from intrinsic value, positioning the portfolio to benefit from compounding growth over time. #proactiveinvestors #LloydCapital #ValueInvesting #Investing #StockMarket #PortfolioManagement #EquityInvesting #ConstellationSoftware #LongTermInvesting #WealthManagement #InvestmentStrategy #hanetf
- Yesterday3 min
Blue Jay Gold launches fully funded 16,000-metre Yukon drill program at Steller Gold project
Blue Jay Gold CEO Geordie Mark joined Steve Darling from Proactive to announce the start of diamond drilling at the company’s 100%-owned Steller Gold Project in Yukon, marking the beginning of its fully funded 2026 exploration campaign. The program has commenced along the Skukum Creek Corridor, with initial drilling focused on the northern silver-gold-rich zone surrounding Raca. The 2026 exploration strategy is designed to expand the footprint of existing high-grade gold and silver resources while testing additional targets using new geological techniques and integrated exploration approaches. Mark explained that the company is combining modern re-logging of historical drill core with advanced spectral analysis, paragenetic studies, and district-scale structural modelling. This work is being integrated with both existing and newly acquired regional geophysical data to improve understanding of the structural controls associated with mineralization across the property. The goal is to better define the large-scale geological architecture of the district, identify key mineralized conduits, and generate a pipeline of future drill targets for 2026 and beyond. To support the scale of the exploration effort, Blue Jay is mobilizing a second drill rig to the project. The company’s fully funded program is expected to include up to 16,000 metres of drilling, allowing multiple target areas to be advanced simultaneously throughout the field season. Management believes the combination of high-grade existing resources, extensive historical data, and modern exploration techniques provides significant potential to expand known mineralization and make new discoveries across the broader Steller Gold Project. Drill results are expected to be released on a rolling basis throughout the remainder of 2026 as exploration activities continue. #proactiveinvestors #bluejaygold #tsxv #jay #StellerGoldProject #YukonMining #GoldExploration #SilverExploration #MiningNews #DrillingProgram #ResourceExpansion #GoldStocks #MineralDiscovery
- 2 days ago6 min
Appia Rare Earths launches 3,300-metre drill program at high-grade Alces Lake project
Appia Rare Earths and Uranium CEO Tom Drivas joined Steve Darling from Proactive to announce the start of mobilization for a 3,300-metre diamond drilling program at the company’s 100%-owned Alces Lake Rare Earth Elements project in northern Saskatchewan. Drivas explained that the 2026 summer exploration program will consist of nine diamond drill holes targeting depths between 300 and 500 metres. The campaign is designed to test several high-priority rare earth element (REE) targets identified through the company’s 2025 ground gravity survey, which refined targets originally outlined by a 2024 airborne gravity gradiometer survey. The targets were selected based on strong geophysical similarities to Appia’s high-grade WRCB mineralized zone and the near-surface Magnet Ridge discovery, both of which have demonstrated significant rare earth mineralization. The drilling program will focus on evaluating the potential continuation of REE-bearing lithological units at depth and along strike within a regional northwest-southeast structural corridor that hosts several of the project’s key mineralized zones. Management believes the program could further expand understanding of the scale and continuity of mineralization across the property while identifying new opportunities for resource growth. The Alces Lake Property is widely recognized for hosting some of the highest-grade rare earth element mineralization discovered in Saskatchewan and has emerged as one of Canada's most significant REE exploration projects. Rare earth elements are critical components in electric vehicles, wind turbines, advanced electronics, defense systems, and other technologies supporting the global energy transition. With drilling now underway, Appia aims to further unlock the potential of the Alces Lake district and advance one of North America's most promising rare earth exploration assets. On the uranium side, Appia is advancing several exploration projects in Saskatchewan's Athabasca Basin region. Drivas highlighted one project that displays multiple geophysical characteristics associated with major uranium deposits and is awaiting interpretation from a recently completed MT survey. The interview also touched on the company's Elliot Lake property in Ontario, which hosts a NI 43-101 resource containing uranium and rare earth elements in a historically productive mining district. #proactiveinvestors #appiarareearthsanduranium #cse #api #otcqb #apaaf #RareEarthElements #AlcesLake #CriticalMinerals #REE #SaskatchewanMining #MiningNews #EnergyTransition #ExplorationDrilling #ResourceDevelopment
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