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Happy Bones, Happy Life

The Missing Piece in Bone Health? Your Gut Microbiome with Emeran Mayer, MD and Margie Bissinger

April 7, 2026·51 min
Episode Description from the Publisher

Did you know your gut microbiome can directly impact your bone health? In this episode, Dr. Emeran Mayer, a renowned gastroenterologist, neuroscientist, and professor at UCLA, reveals how the health of your gut can directly influence your bones, estrogen levels, and overall health. Dr. Mayer explains how diverse fiber sources in your diet can support a healthy microbiome, and he shares fascinating new research on targeted probiotics that could help boost your body's estrogen production. We explore the role of your gut in reducing inflammation and how the microbiome helps recycle estrogen, which is crucial during and after menopause. If you're looking for a holistic approach to bone health, this episode is full of valuable, research-backed advice to improve your gut microbiome and strengthen your bones!   "Microbes thrive on raw fiber. The more you reduce fiber by processing food and overcooking it, the less benefits you get from your intrinsic healing system." ~ Emeran Mayer, MD   In this episode: - [02:05] - Why Dr. Mayer is passionate about microbiome science - [05:15] - The importance of sufficient and diverse fiber for a healthy microbiome - [11:25] - The science behind short-chain fatty acids and their anti-inflammatory effects - [16:11] - How to increase the variety of your fiber intake - [20:00] - Dr. Mayer's thoughts on supplements  - [26:52] - The role of gut microbiome in bone health and recycling estrogen  - [35:58] - Probiotics-rich foods and how they can help boost your health - [43:11] - Dr. Mayer's latest research on the gut-brain connection - [45:39] - Learn more about Dr. Mayer's work   Resources - Fullscript Supplements at a Discounted Price - https://tinyurl.com/supplementsforless - Dr. Mayer's website - https://emeranmayer.com/ - Dr. Mayer's olive oil with high polyphenol content - https://collabs.shop/prt6nd  - Margie's on-demand class with Anu Simh on how to eat to improve your microbiome: The Bone Building Kitchen - https://www.happyboneshappylife.com/the-bone-building-kitchen-on-demand-class   More about Margie - Website - https://margiebissinger.com/  - Facebook - https://www.facebook.com/p/Margie-Bissinger-MS-PT-CHC-100063542905332/  - Instagram - https://www.instagram.com/margiebissinger/?hl=en    DISCLAIMER – The information presented on this podcast should not be construed as medical advice. It is not intended to replace consultation with your physician or healthcare provider. The ideas shared on this podcast are the expressed opinions of the guests and do not always reflect those of Margie Bissinger and Happy Bones, Happy Life Podcast. *In compliance with the FTC guidelines, please assume the following about links on this site: Some of the links going to products are affiliate links of which I receive a small commission from sales of certain items, but the price is the same for you (sometimes, I even get to share a unique discount with you). If I post an affiliate link to a product, it is something that I personally use, support, and would recommend. I personally vet each and every product. My first priority is providing valuable information and resources to help you create positive changes in your health and bring more happiness into your life. I will only ever link to products or resources (affiliate or otherwise) that fit within this purpose.

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