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Gladden Longevity Podcast: Daily Summaries Delivered
by Gladden Longevity Podcast
On this podcast focused on health and human longevity, Dr. Jeffrey R. Gladden, MD, FACC, and Steve Reiter examine the latest scientific research, technology, and biohacks to uncover the truth about the human body's potential for extending both life and health span well past what most people accept as biological facts.
Latest Episodes
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- 3 days ago42 min
The Metabolic Approach to Psychiatry - Episode 357
In this episode, Dr. Jeffrey Gladden and psychiatrist Dr. Matt Bernstein discuss the evolving landscape of mental health treatment. Bernstein shares his extensive experience in psychiatry, particularly with serious mental health conditions, and highlights the limitations of traditional medication approaches. He advocates for a more holistic view that considers metabolic health and mitochondrial function as critical components in understanding and treating mental health issues. The conversation also delves into the benefits of the ketogenic diet, cognitive flexibility, and the complexities of medication management in psychiatric care. In this conversation, Dr. Gladden and Matt Bernstein explore the intricate relationship between mental health, metabolism, exercise, and the role of psychedelics in therapy. They discuss the negative metabolic impacts of psychotropic medications, the significant benefits of exercise for mental health, and the importance of understanding individual genetics in managing depression. The conversation also delves into the role of lactate in brain health, mitochondrial function, and the potential of psychedelic therapies for personal transformation. Ultimately, they emphasize the need for a holistic approach to health that encompasses physical, mental, and spiritual well-being. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Matt Bernstein has 26 years of experience in psychiatry. · He works with serious mental health conditions like bipolar disorder and schizophrenia. · Traditional psychiatric medications often lead to metabolic and neurological side effects. · Anhedonia is a significant issue in mental health, meaning a lack of pleasure. ·<span style="font
- 1 weeks ago6 min
Dr. Jeffrey Gladden's Daily Longevity Routine: How He Trains for Strength, Mobility, and Energy - Episode 356
Dr. Jeffrey Gladden shares the full routine he uses to support longevity day to day, from his first hour in the morning to his weekly, monthly, and yearly training priorities. The episode is useful if you want a practical look at how he combines recovery, movement, therapy, and mindset to stay active and sharp. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways In this episode, Dr. Gladden explains why he never wakes up to an alarm and instead lets his body set his sleep schedule. He starts his day with thyroid medication, then uses the first 30 minutes for journaling, gratitude, daily goals, and affirmations. He describes music as part of his routine, including picking up the guitar each morning to write, doodle, and release emotional energy. He rotates his exercise instead of repeating the same workout daily, using mountain biking, running, elliptical work, and an elevation training mask to build lung capacity. He emphasizes getting outside as often as possible and treating movement as a daily non-negotiable. He stacks cardio with sauna when possible, often doing both before starting work. He does not begin his workday until 10 a.m., using the morning to train, recover, and mentally prepare for clients and emails. He trains mobility as seriously as cardio and resistance work, including floor work, crawling, burpees, and deep squat practice. He mentions monthly therapies such as plasmapheresis, Eboo, red light, and ozone sauna as part of his longer-cycle routine. He frames longevity as a yearly performance target: stronger, faster, fitter, sharper, and more mobile than the year before. He stresses treating injuries immediately and using regenerative therapies and peptides to reduce downtime and slow the acceleration of aging. He believes many people stop short in training and need to lean into hard effort rather than backing off too early. Chapters 00:00 - Dr. Jeffrey Gladden's longevity philosophy and "100 is the new 30" 00:34 - Waking without an alarm and starting with thyroid medication 01:0
- 2 weeks ago27 min
Navigating the World of 503A and 503B Pharmacies - Episode 355
In this episode of the Gladden Longevity Podcast, Dr. Gladden hosts Joshua Fritzler, President of Olympia Pharmaceuticals, and Nicole Snow to discuss the intricacies of compounding pharmacies, focusing on the differences between 503A and 503B pharmacies, the role of compounding in personalized medicine, and the current landscape of peptides and FDA oversight. The conversation highlights the importance of safety, regulation, and quality assurance in compounded medications, providing listeners with a comprehensive understanding of how these pharmacies operate and their significance in modern healthcare. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Compounding pharmacies create personalized medications not commercially available. · 503A pharmacies serve individual patients with specific prescriptions. · 503B pharmacies produce larger batches for clinics and have stricter regulations. · Compounded medications can be tailored to avoid allergens or intolerances. · FDA does not approve compounded medications, but regulates the pharmacies. · <span style="mso-ansi-language: EN
- 3 weeks ago32 min
Preventing Heart Disease: A New Paradigm - Episode 354
In this conversation, Dr. Jeffrey Gladden and Dr. Philip Ovadia discuss the critical intersection of cardiology and longevity, emphasizing the need for a shift from treating heart disease to preventing it. They explore personal transformations, the role of diet, particularly low-carb and carnivore diets, and the importance of understanding insulin resistance in relation to heart health. The discussion also highlights advancements in cardiovascular diagnostics and the necessity for early detection and patient education to combat heart disease effectively. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · The focus on longevity in cardiology is essential. · Preventing heart disease is more effective than treating it. · Personal health transformations can lead to professional insights. · Dietary changes can significantly impact heart health. · Insulin resistance is a major factor in heart disease. · Understanding the role of cholesterol is crucial. <span style= "font-family: Symbol; mso-fareast-font-famil
- Aug 20, 202658 min
Unraveling Alzheimer's: The Pathobiome Connection - Episode 353
Dr. Gladden and Nikki Schultek explore the intricate links between Alzheimer's disease, infections, and the pathobiome. Nikki shares her personal journey through chronic illness and how it led her to advocate for a better understanding of the role of infections in autoimmune and neurodegenerative diseases. They discuss the importance of a systems biology approach to healthcare, emphasizing the need for collaboration among specialists to address complex health issues. The conversation highlights the interplay between genetics, infections, and chronic diseases, and the potential for future research to uncover new treatment avenues. In this conversation, Dr. Gladden and Nikki Schultek discuss the integration of systems biology in health optimization, emphasizing the importance of collaboration in research and the role of AI in uncovering health insights. They explore the microbiome's impact on neurodegenerative diseases, hormonal influences on aging, and the necessity of a strong therapeutic connection in patient care. The discussion also touches on economic incentives in healthcare and the urgent need for a comprehensive approach to chronic disease research, likening it to a Manhattan Project. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Nikki's journey into the world of Alzheimer's began with her own health struggles. · Infections can drive autoimmune states and neurodegenerative diseases. · The medical system often operates in silos, complicating patient care. · Chronic infections may be overlooked in patients with complex symptoms. · A systems biology approach is essential for understanding chronic diseases. <!-- [if !
- Aug 13, 202642 min
From Reactive Care to Preventive Longevity - Episode 352
In this episode, Dr. Gladden speaks with Dr. Hany Demian about the shift from reactive medicine to prevention, personalization, and longevity-focused care. Dr. Hany shares how his journey through breast surgery, emergency medicine, and chronic pain management led him to a more systems-based approach to health, aging, and healing. They discuss why aging may be better understood as a condition, how patient empowerment changes outcomes, and why nervous system regulation, stress reduction, and individualized care matter as much as diagnostics and therapies. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Dr. Hany says many chronic conditions are the result of biology drifting over time, not just isolated bad luck · He emphasizes that healthy patients are rarely rewarded in the current billing system · His approach is to assess where a patient's biology is now and how far it has diverged from a healthier baseline · Lifestyle foundations like sleep, nutrition, exercise, and supplements are treated as the first levers · Dr. Hany believes aging should be classified as a diagnosable, measurable condition · <span st
- Aug 6, 202639 min
The Exponential Curve of Aging - Episode 351
Michael Clinton and Dr. Gladden explore the concept of longevity and the evolving perception of aging. They discuss the importance of viewing the second half of life as an opportunity for growth and adventure rather than a decline. The discussion covers the significance of role models, the idea of life layering to build identities beyond work, the necessity of movement and engagement, and the architectural approach to health through five circles. They also touch on the generational transfer of health and the importance of community and connection in combating loneliness and mental health issues. In this conversation, Michael Clinton and Dr. Gladden explore the interconnected themes of community support, generational trauma, the impact of aging, and the power of creativity. They discuss how understanding one's family history can help in addressing mental health issues and the importance of embracing aging positively. The dialogue emphasizes the significance of co-creation and friendships across generations, highlighting how these relationships can enhance joy and fulfillment in life. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · We're living 21st century lives in 20th century constructs. · Aging is an exponential decline, not a linear decline. · If you're 65 and healthy, you're gonna live to 95. · Life layering is building another identity beyond profession. · The number one natural medicine is movement. <!-- [if !supportL
- Jul 30, 202643 min
Unlocking the Secrets of Nutrigenomics - Episode 350
In this conversation, Dr. Gladden and Annelie Smith explore the intersection of genetics and nutrition, emphasizing the importance of personalized approaches to health. They discuss the evolution of nutrigenomics, the role of AI in developing tailored health plans, and the complexities of hormonal balance as influenced by genetics. Annelie shares insights from her clinical experience, highlighting the need for a systems biology approach to understand the intricate relationships between genes, hormones, and overall health. The discussion also touches on future directions in genetic testing and the potential for more accessible and actionable insights for individuals. In this conversation, Dr. Gladden and Annelie Smith delve into the complexities of hormone replacement therapy, emphasizing the importance of understanding hormonal pathways and the role of genetics. They discuss how stress impacts hormonal balance and the significance of reprogramming the nervous system for better health outcomes. The conversation also highlights the relevance of nutrigenomics in personalized nutrition and the powerful benefits of sulforaphane. Finally, they explore the value of genetic testing for optimizing health and wellness. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Nutrigenomics provides insights into personalized nutrition. · Understanding genetics can enhance dietary recommendations. · AI is transforming the landscape of personalized medicine. · Systems biology offers a holistic view of health. · Patient engagement is key to successful health interventions. <span style= "font-family: Symbol; mso-fareast-font-family: Symbol; mso-bidi-font-family: Symbol
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About Gladden Longevity Podcast
On this podcast focused on health and human longevity, Dr. Jeffrey R. Gladden, MD, FACC, and Steve Reiter examine the latest scientific research, technology, and biohacks to uncover the truth about the human body's potential for extending both life and health span well past what most people accept as biological facts.
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