Gladden Longevity Podcast

The Metabolic Approach to Psychiatry - Episode 357

September 17, 2026·42 min
Episode Description from the Publisher

In this episode, Dr. Jeffrey Gladden and psychiatrist Dr. Matt Bernstein discuss the evolving landscape of mental health treatment. Bernstein shares his extensive experience in psychiatry, particularly with serious mental health conditions, and highlights the limitations of traditional medication approaches. He advocates for a more holistic view that considers metabolic health and mitochondrial function as critical components in understanding and treating mental health issues. The conversation also delves into the benefits of the ketogenic diet, cognitive flexibility, and the complexities of medication management in psychiatric care. In this conversation, Dr. Gladden and Matt Bernstein explore the intricate relationship between mental health, metabolism, exercise, and the role of psychedelics in therapy. They discuss the negative metabolic impacts of psychotropic medications, the significant benefits of exercise for mental health, and the importance of understanding individual genetics in managing depression. The conversation also delves into the role of lactate in brain health, mitochondrial function, and the potential of psychedelic therapies for personal transformation. Ultimately, they emphasize the need for a holistic approach to health that encompasses physical, mental, and spiritual well-being. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!    Takeaways ·       Matt Bernstein has 26 years of experience in psychiatry. ·       He works with serious mental health conditions like bipolar disorder and schizophrenia. ·       Traditional psychiatric medications often lead to metabolic and neurological side effects. ·       Anhedonia is a significant issue in mental health, meaning a lack of pleasure. ·<span style="font

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