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by Shane Farnsworth
Escaped Sapiens is a long-form podcast exploring science, intelligence, exploration, and the edges of human understanding through in-depth conversations with researchers, thinkers, and field experts.
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What determines who you become: your genes, your environment, or something else entirely? I originally the answer lay in our environment and DNA, full stop. But it turns out there's a third ingredient. Our DNA doesn't hold enough information to specify all of the the various connections in our brain. In a certain sense the DNA specifies a charicature, and the process of development itself fills in the details. This process starts at conception, such that even two people growing with identical DNA and environment will nevertheless end up with different personality traits, intelligence, etc. In this conversation I speak with Neurogeneticist Kevin Mitchel (Trinity College Dublin, author of Free Agents and Innate) about how our brains develop. He spells out the implications of the developmental process of the brain for our personalities, medical conditions, and intelligence, consciousness, and free will. Correction: At 1:57:02, the claim about XYY syndrome and violence was misleading. Some studies have found a modest association with lower average IQ, but the evidence does not support XYY making someone inherently more violent. ►Watch on YouTube: https://www.youtube.com/watch?v=EohgJnp6bNQ&list=PLnE3V9mcAvmbGgs15Z0LkfHv0_1Hm5i9Z&index=1 ►Find out more about Kevin's work: www.kjmitchell.com ►Check out Kevin's books: https://press.princeton.edu/books/hardcover/9780691173887/innate https://press.princeton.edu/books/hardcover/9780691226231/free-agents
We can't put a real black hole in a laboratory, but we can recreate some of its most important physics. In this interview I speak with Bill Unruh, one of the pioneers of analog gravity. The idea is fascinating: Usually we model gravity using equations and computer simulations, but there is another way. Rather than a gravitational black hole that can trap light from escaping, you can instead build a black hole using the flow in a fluid to trap sound from escaping. Such models really do mimic many of the properties predicted by the equations that describe black holes. Unruh explains how a waterfall can act as a sonic black hole, creating an analogue of a black hole event horizon where sound waves can become trapped. In the lab, such analog systems have been built using water, but also Bose–Einstein condensates. One hope is to show that analog black holes sponateously emit sound quanta in exactly the same way that Hawking radiation is proposed to be emitted from Black holes. In particular, a key goal is to show that such radiation is `thermal', which would mean that it carries the least amount of information possible just as predicted by Hswking for black holes. One of the key reasons for being interested in analog gravity, is that it can provide intuition about horizons and other aspects of gravitational systems that we can't explore in the lab. In this interview I ask Bill what intuition he has gained for one of the key paradoxes in gravitational physics that researchers are currently arguing over: The Black Hole Information Paradox. In particular, what happens to the information contained in matter that falls into a black hole? Can Hawking radiation carry that information back out? We also discuss what actually happens inside a black hole. Does the singularity represent a genuine physical feature, or does it signal that our current theory of gravity has reached its limits? ►Watch on Youtube: https://www.youtube.com/watch?v=DzNAGllVWjo&list=PLnE3V9mcAvmYosrFCguPfGnFeI_CChb1j&index=1 ►Find out more about Bill's work: https://quantumgravitysociety.org/science_advisors/william-unruh/ https://news.ubc.ca/expert/william-unruh/ #BlackHoles #HawkingRadiation #QuantumGravity #AnalogGravity #Physics #QuantumMechanics #GeneralRelativity #StephenHawking #BlackHoleInformationParadox #TheoreticalPhysics #cosmology This publication is based upon work from COST Action RQI CA23115, supported by COST (European Cooperation in Science and Technology). COST is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. For more information see: www.cost.eu .
Our understanding of gravity and black holes is currently in a funny spot that looks a little similar to how physics in general looked before quantum mechanics. Before quantum mechanics, scientists were puzzled by the stability of atoms. Shouldn't the negatively charged electrons simply fall into the positively charged nucleus? Also, the electrostatic force between charges was known to increase the closer two charged objects were to one another, and by naive extrapolation, this force should become infinite as the distance between objects goes to zero. This is known as a `singularity' in the theory. Singularities are usually a sign that our theory is being extrapolated beyond where it is applicable. Quantum mechanics held the solution to the puzzle: electrons don't spiral around the nucleus; they sit in quantum orbits that can only take on certain discrete levels. In our current understanding of gravity, there are objects predicted by the theory known as black holes. But just like with `classical' atoms, these objects are pretty weird. They have singularities right at the center, and just like the electrons orbiting an atomic nucleus, the classical theory of gravity says that matter should spiral into a black hole to meet the singularity. On the way, they cross an event horizon from which they can never return, and which shields anyone from looking into the black hole. The singularity is an indication that our classical theory of gravity is somehow breaking down. But where? If we try to merge quantum mechanics with black holes, a clue arises: `Hawking' radiation is predicted by the merger to emanate from the black hole horizon, and this radiation leads to the evaporation of black holes, and the loss of all the information of anything that fell in. But this behavior appears to break quantum mechanics because in quantum theory, information cannot be destroyed. It can be scrambled, transformed, hidden, but never fundamentally erased. This is the black hole information paradox: the merger of our best gravitational theory and quantum theory seems to lead to information loss, which is incompatible with quantum theory. In this episode of the podcast, I speak with theorist Niayesh Afshordi. He suggests that the black hole information paradox arises because we are extrapolating our equations beyond where they make sense. His suggestion is a little unorthodox: black holes have no center. The horizon must be replaced with a surface, beyond which there is nothing. I speak with him to try to understand his suggestion. ►Watch on Youtube: https://www.youtube.com/watch?v=68qwzsjmoxU&list=PLnE3V9mcAvmYosrFCguPfGnFeI_CChb1j&index=1 ►Find out more about Niayesh's work: https://nafshordi.com/ ►Follow Niayesh on Twitter: @nafshordi #BlackHoles, #QuantumMechanics, #QuantumPhysics, #HawkingRadiation, #BlackHoleInformationParadox, #Gravity, #TheoreticalPhysics, #Physics #NiayeshAfshordi, #GeneralRelativity This publication is based upon work from COST Action RQI CA23115, supported by COST (European Cooperation in Science and Technology). COST is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. For more information see: www.cost.eu.
The black hole information paradox sits at the intersection of quantum mechanics and general relativity, two of our most successful theories of nature. According to classical general relativity, anything that crosses the event horizon of a black hole is lost to the outside universe forever. Black holes are almost featureless. It doesnt matter if you build one from tea pots, or elephants, the information of what fell in is hidden forever. But quantum mechanics tells a different story. In quantum theory, information cannot be destroyed. It can be scrambled, transformed, hidden, but never fundamentally erased. So what happens when these two ideas collide in the most extreme environment in the universe? If a black hole forms from a star and later evaporates through Hawking radiation, what happens to the information about everything that fell in? Does it come back encoded in the radiation? Does it remain trapped forever? Or does physics itself break down at the boundary? To make this concrete, imagine throwing a book into a black hole. If the black hole eventually evaporates completely, the total mass returns to the universe as radiation, but what happens to the detailed information inside that book? The words, the structure, the arrangement of matter that defined it? Depending on how you answer that question, you either preserve one of the deepest principles in quantum theory, or you are forced to accept that something fundamental about our understanding of reality is incomplete. In this conversation, I speak with theoretical physicist Carlo Rovelli, one of the leading voices in quantum gravity, to explore the black hole information paradox. He outlines what the paradox is, explains where he belives many physicists get themselves confused, and puts forward his own solution to the paradox. ►Watch on YouTube: https://youtu.be/vjsof8VfOM0 ►You can find out more about Carlo's work here: https://www.cpt.univ-mrs.fr/~rovelli/ ►Follow Carlo on Twitter: @carlorovelli This publication is based upon work from COST Action RQI CA23115, supported by COST (European Cooperation in Science and Technology). COST is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. For more information see: www.cost.eu
What makes a bioweapon effective? What are researchers actually capable of creating in the lab? What pathogens are kept in storage? How realistic is a large scale catestrophic attack using a bioweapon? In this conversation I speak with Kevin Esvelt, who is an associate professor at the MIT Media Lab, where he leads the Sculpting Evolution Group in advancing biotechnology safely. Kevin was one of the pioneering researchers behind gene drive technology. In 2013, recognizing the potential dangers of the technology, he and his colleagues chose to break with scientific tradition by revealing their findings and calling for open discussion and safeguards before building the first CRISPR-based gene drive system and demonstrating reversibility in the laboratory. Kevin now focuses on accelerating beneficial advances while safeguarding biotechnology against mistrust and misuse. Projects include building catalytic platforms for directed evolution, pioneering new ways of developing ecotechnologies with the guidance of local communities, developing early-warning systems to reliably detect any catastrophic biological threat, applying cryptographic methods to enable secure and universal DNA synthesis screening, and advising policymakers on how best to mitigate global catastrophic biorisks. We discuss the state of the art in pathogen development, as well as the tools available to safegaurd humanity. ►Watch on Youtube: https://youtu.be/SLj8vwliQp0 ►You can find out more about Kevin's work here: https://www.sculptingevolution.org/kevin-m-esvelt ►Follow Kevin on X: @kesvelt
Our reality is increasingly being filtered through AI. People now defer to AI chatbots for more and more of their information needs, and google searches return AI generated overviews as their top responses. While this may have its benefits, problems are starting to arise as our interactions with AI are becoming more comprehensive, immersive, and emotionally meaningful. Researchers are begining to warn that AI might be contributing to the development of delusional beliefs and psychotic experiences. Reports of what has been called “AI-associated psychosis” have raised concerns about people becoming intensely attached to AI systems, interpreting conversations with them as uniquely meaningful, or developing beliefs that are reinforced through repeated interactions. Real world examples include people believing that AI is sending them hidden messages, that they have a special mission, that the have made new mathematical discoveries, and that AI is awakening. There have even been cases involving violence and death in the real world. So the question is: What is going on? Can we seperate the real world cases of AI psychosis from the media headlines? In this conversation I speak with Dr. Joseph Pierre, Professor of Psychiatry at the University of California, San Francisco, and the Unit Chief of the Langley Porter Psychiatric Hospital Adult Inpatient Unit. He has extensive clinical experience working with individuals with psychotic disorders, as well as research experience participating as a primary investigator and collaborator for clinical trials in schizophrenia and early intervention for young persons at high risk for psychosis. His academic work explores the "grey area" between psychopathology and normality with a focus on delusion-like beliefs including conspiracy theories. We discuss what AI-associated psychosis means, the evidence behind these emerging concerns, the psychology of delusional thinking, how AI systems may influence human cognition, and what we should-and should not-conclude about the risks of increasingly powerful conversational AI. ►Watch on YouTube: https://youtu.be/nniFFxTU5Tw Find out more about Joe's work here: https://profiles.ucsf.edu/joseph.pierre ►Read Joe's book: https://global.oup.com/academic/product/false-9780197765272?cc=nl&lang=en& https://www.amazon.nl/False-Mistrust-Disinformation-Motivated-Reasoning/dp/0197765270 ►Follow Joe on X: @psychunseen
Fertility is dropping worldwide. Across much of the West, total fertility rates now sit around 1.4-1.5 births per woman, well below the replacement level of 2.1. That implies a long-run population decline in the absence of immigration: each generation is smaller than the last, compounding over time. To make this concrete, if you take a representative group of 100 adults today and project forward under a constant fertility rate of about 1.5 births per woman, that group would, on average, correspond to roughly 50 grandchildren two generations later-an effective halving of the population. In South Korea the effect is far more extreme. With a total fertility rate around 0.7-0.8 births per woman, the same kind of projection implies that 100 adults today would correspond to only about 10-15 grandchildren on average two generations later. In other words, each generation is dramatically smaller than the one before it, compounding rapidly over time. So what does this actually mean? What happens when societies move from growth to sustained generational decline? How do pension systems function when the ratio of workers to retirees collapses? What happens to economic growth, political stability, cultural continuity, identity, and population composition in societies that are rapidly aging and shrinking at the same time? In this conversation, I speak with Lyman Stone, Senior Fellow and Director of the Pronatalism Initiative at the Institute for Family Studies, and Director of Research at Demographic Intelligence. We discuss the data behind the fertility crash, the drivers of this global shift, its long-term implications, and the policy options that might-or might not-reverse it. ►Watch on YouTube: https://youtu.be/i-vgPaxB-Wg ►You can find out more about Lyman's work here: https://ifstudies.org/about-us/lyman-stone#:~:text=Lyman%20Stone%20is%20a%20Senior,with%20a%20Population%20Dynamics%20specialization.
In evolutionary terms, the last Ice Age was just yesterday. We narrowly missed witnessing creatures like woolly mammoths, short-faced bears, glyptodons, and dire wolves. The late Pleistocene, spanning roughly 50,000 to 12,000 years ago, is marked by the extinction of most large terrestrial animals outside of Africa, likely driven by a combination of climate change and the expansion of modern humans. In this conversation, I speak with paleontologist and Associate Professor of Anatomy at Des Moines University, Julie Meachen. She leads ongoing research at Natural Trap Cave, where she and her team excavate Ice Age mammals each summer. Their work aims to understand how climate change influenced both the morphology and genetics of these animals. By analyzing microfaunal remains and pollen records, they also reconstruct Pleistocene climate conditions in mid-latitude North America. Recently, colossal bioscience announced what it described as the “de-extinction” of the dire wolf. While that claim did not fully hold up, the underlying science is still remarkable. In our discussion, Julie explains what we know about the late Pleistocene ecosystem at the time of the dire wolf’s extinction, and what fossil evidence reveals about these animals. We also examine Colossal’s announcement, considering whether it was aimed less at the scientific community and more at the public and potential investors. Viewed in that light, the real value of reviving charismatic species like the woolly mammoth or dire wolf may not lie in the animals themselves. Instead, their greatest contribution could be as ambassadors, capturing public imagination and helping drive the development of technologies for genetic rescue and conservation. ►Watch on YouTube: https://youtu.be/c4lvsreJ-WU ►You can find out more about Julie's work here: https://scholar.google.com/citations?user=-hdi3IUAAAAJ&hl=en https://www.dmu.edu/directory/profile/julie-meachen/
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Escaped Sapiens is a long-form podcast exploring science, intelligence, exploration, and the edges of human understanding through in-depth conversations with researchers, thinkers, and field experts.
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