Mind & Matter

Reversing Alzheimer's & Neurodegeneration: Latest Science | Andrew Pieper | Episode 290

April 24, 2026·1h 24m
Episode Description from the Publisher

Send us Fan Mail A metabolic view of Alzheimer's disease & the recent discovery of compounds that reverse advanced disease symptoms in mouse models by restoring mitochondrial health. TOPICS DISCUSSED: Classic Alzheimer’s pathology: amyloid plaques and tau tangles identified over 120 years ago, long assumed to drive irreversible neuron loss.Limitations of amyloid focus: plaques appear in some cognitively normal brains; antibody therapies have shown limited clinical benefit.Metabolic perspe...

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