Omega Polyunsaturated Fats in Inflammation | Philip Calder | Episode 291

Send us Fan Mail How dietary fatty acids regulate the initiation, propagation, and resolution of inflammation. TOPICS DISCUSSED: Parenteral nutrition history: IV nutrition evolved from soybean oil alone in the 1960s to complex blends including fish oil as the biology of ω-3s became understood.Three phases of inflammation: Initiation, propagation (driven by ω-6–derived prostaglandins and leukotrienes), and active resolution (driven by ω-3-derived resolvins and protectins).Pro-resolving mediato...