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by David Hunter, PhD, FRACP (Rheum)
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- 1 weeks ago41 min
Do you really need surgery for your knee osteoarthritis? with Dr Howard Luks (2021)
The number of surgical procedures for musculoskeletal diseases such as osteoarthritis has increased exponentially over the past years, some of which are unnecessary and leave patients no better off than they were before. Knee replacement surgery can be a wonderful and cost-effective treatment for end-stage osteoarthritis but only when less invasive treatments have failed. There are many factors driving the alarming rates of increased surgery ranging from system-level factors such as inadequate reimbursement for physiotherapy treatment to personal-level factors such as individual beliefs and education of patients and their health care providers. Frequently referrals are made to surgeons as primary care doctors feel there is nothing more they can do. If you are referred it is important to be prepared for what that consultation will involve and to consider whether you truly want/ need surgery.On this episode of Joint Action, we are joined by Dr Howard Luks to discuss this topic.Dr. Howard Luks is a Board-Certified Orthopaedic Surgeon and Sports Medicine specialist. Howard graduated from New York Medical College and completed his Orthopaedic Surgery residency in 1996 and a fellowship in Sports Medicine at the Hospital for Joint Diseases in NYC in 1997. His focus is on injuries that involve the shoulder, knee, and elbow. He is the Chief of Sports Medicine and Arthroscopy at New York Medical College and Advanced Physician Services.CONNECT WITH HOWARDWebsite: https://www.howardluksmd.com/Podcast: https://www.howardluksmd.com/podcast/the-paul-and-howard-show/CONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- 3 weeks ago29 min
Finding Responders: The Next Phase of OA Biomarkers with Dr Virginia Kraus, Dr Peter Mesenbrink, and Dr Jamie Collins
Can identifying the right patients and the right endpoints transform how we test new osteoarthritis treatments? On this week's episode of Joint Action, we unpack what the FNIH Biomarkers Consortium has learned so far, and how their latest phase aims to deliver biomarkers that can make disease-modifying OA drug trials smaller, faster, and more likely to succeed.Dr. Virginia Byers Kraus is a Professor of Medicine, Pathology, and Orthopaedic Surgery at Duke University School of Medicine. A rheumatologist and translational scientist, her research focuses on osteoarthritis and biomarker development as part of the international FNIH Biomarkers Consortium.Peter G. Mesenbrink, Ph.D., is Executive Director of Biostatistics at Novartis and industry co-chair of the FNIH Biomarkers Consortium. With expertise in adaptive trial design, surrogate endpoint development, and data sharing policy, he is a frequent collaborator across industry, regulatory, and academic communities.Dr. Jamie Collins is a biostatistician at Brigham and Women's Hospital and Associate Professor of Orthopaedic Surgery at Harvard Medical School. As lead statistician for the FNIH OA Biomarkers Consortium, her research focuses on strengthening osteoarthritis clinical trials through innovative trial design and prognostic enrichment.RESOURCESFNIH: Treatment Response Biomarkers for Disease Modifying Osteoarthritis Drugs (DMOADs)CONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Apr 12, 202638 min
Defining the early-stage OA patient: the EsSKOA initiative with Dr Armaghan Mahmoudian
What does it actually mean to have 'early-stage' osteoarthritis, and does catching it sooner really make a difference? On this week's episode of Joint Action, learn more about early-stage knee osteoarthritis, how it's defined, and why the EsSKOA initiative is changing the way we identify and understand the condition in its earliest phases.Dr. Armaghan Mahmoudian is an Assistant Professor of Movement Sciences and Health at the University of West Florida, where she teaches anatomy and physiology, biomechanics, and research methods, and co-directs the biomechanics and motor learning laboratory. As a clinician-scientist, her research focuses on understanding disease mechanisms and their impact on function and quality of life, with a particular interest in personalised medicine and disease prevention in an ageing population.RESOURCESEsSKOA InitiativeJournal article Reframing early-stage symptomatic knee osteoarthritis (EsSKOA): A strategic lens for trial designCONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Mar 29, 202634 min
The evidence behind knee bracing with Dr Melanie Holden
On this week's episode of Joint Action, learn more about how knee braces work, who they help and how they can improve pain and function for people with knee osteoarthritis. Melanie Holden is a Chartered Physiotherapist and the Professor of Musculoskeletal Rehabilitation at the School of Medicine at Keele University. Her current research focuses on how to best manage musculoskeletal pain through rehabilitation using non-drug, non-surgical treatments.Her mission is to create high-quality, innovative research that improves patient care. She is an expert in a wide range of research methods, and she involves patients and the public at every stage of her research, to ensure that it reflects real-world needs and experiences.RESOURCESJournal articleProvision of knee bracing for knee osteoarthritis (PROP OA): multicentre, parallel group, superiority, statistician blinded, randomised controlled trialCONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Mar 15, 202636 min
Counting the cost: osteoarthritis and workforce productivity with Dr Jason Jin and Prof Ilana Ackerman
Knee osteoarthritis doesn’t just affect joints—it can limit people’s ability to participate fully in work and daily life, shaping their long‑term wellbeing and productivity. In this week's episode of Joint Action we are joined by Jason Jin and Ilana Ackerman to explore how knee osteoarthritis influences workforce participation.Dr Xingzhong (Jason) Jin is a conjoint research fellow at UNSW and the managing director of Precision Statistics Medtech Consulting. He is a musculoskeletal epidemiologist and health data scientist with a desire to bridge the gap between research and real-world healthcare impacts. Professor Ilana Ackerman is a Research Professor at the School of Public Health and Preventive Medicine at Monash University and Deputy Director of the Musculoskeletal Health Unit. She is a musculoskeletal epidemiologist and an experienced orthopaedic physiotherapist and has led an important program of clinical and population-based research designed to quantify the personal and societal burden of hip and knee osteoarthritis, forecast trends in arthritis and joint replacement surgery, and evaluate the outcomes of joint replacement. She has also been involved in the development of multiple policy and guideline initiatives for osteoarthritis.RESOURCESJournal articlesLoss of Productivity-Adjusted Life-Years in Working-Age Australians Due to Knee Osteoarthritis: A Life-Table Modeling ApproachCONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Mar 1, 202622 min
The sleep-pain connection with A/Prof Michelle Hall
Why does a bad night’s sleep make everything hurt more? On this week's episode of Joint Action, we are joined by A/Prof Michelle Hall to explore the cycle between sleep and pain and some practical strategies to help regain both rest and relief.Michelle Hall is an Associate Professor within Sydney Musculoskeletal Health and the School of Health Sciences at the University of Sydney. A leading expert in hip and knee osteoarthritis, Michelle's research focuses on lifestyle strategies-including exercise, sleep, and bracing-to reduce pain and improve quality of life. Her work has produced more than 120 peer-reviewed publications, and she currently leads multi-site clinical trials across Australia and the United States. RESOURCESThisWayUp - Online Mental Health TreatmentCONNECT WITH USNaia Health: https://www.naiahealth.com.au/st-leonards-hubJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Feb 15, 202638 min
Osteoarthritis research advances in 2025 with David Hunter and Anne-Marie Malfait
Hear from the co-editors-in-chief of Osteoarthritis and Cartilage journal on what they thought were the latest advances in osteoarthritis research in 2025.Anne-Marie Malfait, MD, PhD, is Professor of Medicine and the Klaus E. Kuettner, Chair of Osteoarthritis Research at Rush University. She is co-Editor-in-Chief of Osteoarthritis and Cartilage journal alongside David Hunter.RESOURCESDavid's papers Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled trial The Cost-Effectiveness of Semaglutide and Tirzepatide for Patients With Knee Osteoarthritis and ObesityAnne-Marie's paperFM-dye inhibition of Piezo2 relieves mechanically evoked pain in mouse models of acute inflammatory and osteoarthritic knee painAssociation of Synovial Innate Immune Exhaustion With Worse Pain in Knee OsteoarthritisLipidomics unravels lipid changes in osteoarthritis articular cartilageCONNECT WITH USJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
- Feb 1, 202627 min
Tai Chi for the knees with Dr Julia Zhu
Tai Chi is a gentle, low-impact exercise that combines slow, controlled movements with balance and mindfulness. In this week’s episode of Joint Action, we are joined by Julia Zhu to discuss the evidence behind Tai Chi and its benefits for people living with knee osteoarthritis.Julia Zhu is a physiotherapist and PhD student at the Centre for Health, Exercise & Sports Medicine at the University of Melbourne. She recently submitted her PhD, which focused on developing and evaluating a self-directed online intervention for people with osteoarthritis in a clinical trial, where she developed the RETREAT trial that investigated at the effects of an online Tai Chi program. She has an interest in bridging the gap between research and practice and to drive impact with innovation.RESOURCESMyJoint Tai Chi websiteOnline Unsupervised Tai Chi Intervention for Knee Pain and Function in People With Knee OsteoarthritisThe RETREAT Randomized Clinical TrialCONNECT WITH USJoin one of our trials https://www.osteoarthritisresearch.com.au/current-trialsInstagram: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
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About Joint Action
Joint Action is a podcast hosted by David Hunter.As a consequence of isolation, those living with osteoarthritis related disability may become less fit, more depressed and anxious, more socially isolated and gain weight. It is critical at times like this that people with osteoarthritis have their burden and disability minimised and their knowledge of how to manage the disease enhanced. Join David as he interviews the world's leading experts in osteoarthritis.Professor David Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis. He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney and the Royal North Shore Hospital, Sydney, Australia. He is ranked as the worlds leading expert in osteoarthritis on Expertscape.com since 2014.You can send in your questions to <a href="mailto:hello@jointaction.info"
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