Research Renaissance: Exploring the Future of Brain Science

Rethinking Depression: Why Mental Health Is a Whole-Body Disease

April 29, 2026·49 min
Episode Description from the Publisher

What if depression and anxiety are not just disorders of the brain, but conditions shaped by the entire body? In this episode of Research Renaissance, host Deborah Westphal speaks with Dr. Scott Russo, Director of the Brain Body Research Institute at Mount Sinai, about a major shift underway in mental health science. His work challenges the long-standing brain-only model of psychiatric illness and explores how inflammation, immune signaling, and organ systems interact with the brain to shape ...

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