Research Renaissance: Exploring the Future of Brain Science

The Hidden Genome: How Mitochondrial DNA Shapes Aging and Disease

May 13, 2026·45 min
Episode Description from the Publisher

The Hidden Genome Inside Every Cell Most of us learned that mitochondria are the “powerhouse of the cell.” What we didn’t learn? They carry their own DNA — and that DNA may hold crucial answers to aging, neurodegeneration, and rare childhood diseases. In this episode of Research Renaissance, host Deborah Westphal speaks with Dr. Stefan Isaac, Assistant Professor at Boston University and 2025 Toffler Scholar, about how mitochondrial DNA is organized, regulated, and why its dysfunction may...

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