Freakonomics Radio
671. Why Has There Been So Little Progress on Alzheimer’s Disease?
April 17, 2026·1h 1msoloscience
AI Summary (2-min read)
TLDR
A major investigative report reveals widespread data manipulation and research misconduct in Alzheimer's research, centered on the dominant amyloid hypothesis, raising serious questions about decades of scientific direction, regulatory oversight, and the future of treatment.
THESIS —
A major investigative report reveals widespread data manipulation and research misconduct in Alzheimer's research, centered on the dominant amyloid hypothesis, raising serious questions about decades of scientific direction, regulatory oversight, and the future of treatment.
THESIS —
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Guest
C
Charles Piller
solo on Freakonomics Radio
Mentions
Books, people, and resources mentioned in this episode.
People
Charles Pillerby Charles PillerMatthew SchragSylvain LesnéHao Yan WangEliezer MasliaOthman Grebe
Books
Doctored, Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer'sby Charles Piller
Companies
Cassava Sciences
Topics
Data ScienceEthicsFraudInvestigative JournalismNeuroscienceResearchScientific Method
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