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Clinical Trialblazers: Daily Summaries Delivered
by Parexel
Clinical Trialblazers invites you into the world of biotech leaders as they share the untold stories behind their journeys to bring breakthrough innovations to life. This 10 episode monthly series asks biotech visionaries to explore pivotal moments in their careers and the milestones that shaped their lives. Through unscripted conversations, host Alberto Grignolo dives into the decisions, risks, and accomplishments that define these trialblazers legacies to uncover the heart, grit, and ingenuity driving the future of scientific innovation.
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- 1 weeks ago25 min
From Startup to Global CRO: Joe von Rickenbach on Building Parexel and Transforming Clinical Research
In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Joe von Rickenbach, co-founder of Parexel and a pioneer of the modern clinical research organization (CRO) industry, to discuss his journey from launching a two-person regulatory consulting firm in 1982 to building a global CRO that helped redefine drug development worldwide. Joe reflects on the evolution of clinical trials, the rise of outsourcing and digitization in pharma, and the leadership lessons learned from scaling Parexel over 35 years. He also shares insights on entrepreneurship, navigating major business decisions and the future of AI-enabled clinical research, and why trust, relationships, and adaptability remain essential for success in biotech and healthcare innovation. We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen. Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.
- May 5, 202630 min
From Legal to Leadership: Becoming a Successful Biotech CEO with Heather Turner
How do you go from lawyer to biotech CEO? In this episode of Clinical Trialblazers, Heather Turner, CEO of LB Pharmaceuticals, shares her journey from legal counsel to leading a late-stage biotech company. She discusses the mindset shifts required to step into the CEO role, making high-stakes decisions with incomplete data, and balancing risk versus benefit.. Heather brings more than 25 years of experience across biotech and life sciences, with a career that uniquely spans legal, operational, and executive leadership. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Apr 14, 202633 min
From Physician to Biotech CEO: Building High-Impact Clinical Development with Dr. Allison Jeynes
In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Dr. Allison Jeynes, CEO of Nefro Avillion Clinical Development, to explore her remarkable journey from clinician to biotech leader. With over 30 years of experience and a track record that includes the development and approval of nearly 20 drugs, Allison shares how she built a 100% success-rate model in clinical development, and what it takes to sustain excellence in a high-risk industry. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Mar 3, 202628 min
Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO with Paul Garofolo
Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Feb 17, 20261 min
Season 2 is Coming Soon
Clinical Trialblazers will be back soon! Season 2 will bring together a dynamic mix of biotech innovators, executives, and industry leaders to reveal the strategy and teamwork fueling the next wave of clinical breakthroughs. Across 10 new episodes, host Alberto Grignolo will explore high-stakes decisions, unexpected hurdles, and the defining moments that shape both careers and clinical milestones. Season 2 of Clinical Trialblazers is streaming soon wherever you listen to podcasts. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Nov 19, 202522 min
Leadership Lessons from Biotech Innovators
In this season finale of Clinical Trialblazers, host Alberto Grignolo reflects on key insights and themes from conversations with biotech leaders over the past year. From researchers to entrepreneurs to investors, Alberto spoke with a wide range of leaders in the biotech industry, each with a unique perspective on the evolving biotech landscape and advice for aspiring innovators. This episode is just a sampling of the many compelling stories and lessons shared in this remarkable first season. We hope you enjoyed this season of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Oct 14, 202529 min
Building Biotech Success: Insights from Venture Capitalist Dr. Geeta Vemuri
In this episode of Clinical Trialblazers, Alberto sits down with Dr. Geeta Vemuri, Founder and Managing Partner of Agent Capital. They discuss Dr. Vemuri’s journey into venture capital, offering valuable insights on what makes successful biotech companies and CEOs stand out. She also speaks about the critical balance between scientific innovation and strong management teams, the role of capital efficiency in building sustainable companies, the value of board membership, and what excites her about the future of biopharma.We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
- Sep 16, 202528 min
Breaking Barriers in Gene Therapy: Miquel Vila-Perello's Vision for Curing Untreatable Diseases
In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Miquel Vila-Perello, Ph.D. co-founder and CEO of SpliceBio, a gene therapy company focused on treating Stargardt disease. They discuss Miquel's journey from academia to biotech, the challenges of fundraising, the importance of passion and resilience in drug development, and the future of gene therapy. Miquel shares insights on balancing rationality and passion, the differences between academic and industry research, and the significance of building trust with investors.We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi. Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.
About Clinical Trialblazers
Clinical Trialblazers invites you into the world of biotech leaders as they share the untold stories behind their journeys to bring breakthrough innovations to life. This 10 episode monthly series asks biotech visionaries to explore pivotal moments in their careers and the milestones that shaped their lives. Through unscripted conversations, host Alberto Grignolo dives into the decisions, risks, and accomplishments that define these trialblazers legacies to uncover the heart, grit, and ingenuity driving the future of scientific innovation.
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