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What Could Go Right?: Daily Summaries Delivered
by The Progress Network with Zachary Karabell and Emma Varvaloucas
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- Yesterday14 min
Looted Artifacts Returned, Rape Kit Backlogs Slashed, and a Fatal Disease That's Now Treatable
France just passed a landmark law allowing the return of cultural artifacts taken from nations during the colonial era — a long-overdue step nearly a decade in the making. Plus: all 50 U.S. states have now enacted rape kit reform, cutting the national backlog in half; violent crime in major American cities is falling faster than you might expect; and a new drug is doing something doctors have never been able to say about ALS — it's making some patients actually improve. What Could Go Right? is produced by The Progress Network and Kaleidoscope. For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.org Subscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/ Watch the podcast on YouTube: / theprogressnetwork Follow us on X, Instagram, Facebook, TikTok: @progressntwrk Follow Emma on Instagram: https://www.instagram.com/heyemmavarv/
- 6 days ago53 min
The Case for Not Knowing | with Simone Stolzoff
What happens when our biological need for certainty clashes with an increasingly unpredictable world? Simone Stolzoff, author of How to Not Know, joins host Zachary Karabell to discuss why our modern intolerance for uncertainty is fueling a global anxiety crisis. Rather than seeing the unknown as a threat, Stolzoff argues that uncertainty is the fundamental birthplace of scientific breakthroughs, original art, and human progress. Stolzoff and Karabell explore how to navigate everything from the climate crisis and the AI revolution to high-stakes parenting and career choices through the framework that the false certainty we cling to might actually be detrimental to our success. While acknowledging the hard truths of today's world, Stolzoff explains why "action absorbs anxiety" and makes the case for diversifying our identities so we remain adaptable in the face of an unwritten future. What Could Go Right? is produced by The Progress Network and Kaleidoscope. For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.org Subscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/ Watch the podcast on YouTube: / theprogressnetwork Follow us on X, Instagram, Facebook, TikTok: @progressntwrk Subscribe to Zachary’s Substack: www.edgyoptimist.substack.com/
- 1 weeks ago11 min
Gene Therapy Is Giving Blind People Their Sight Back + The UK Bans Smoking Forever and Solar Power From Space
Gene therapy has been quietly pulling off miracles, and this week, it got its Oscars moment. Emma Varvaloucas, Executive Director of The Progress Network, breaks down how a husband-and-wife scientific team's decades-long quest has restored sight to over 100 blind Americans, and how a brand-new drug called Otarmeni just became the first-ever FDA-approved gene therapy for genetic deafness. The science is extraordinary. The price tags, less so.Plus: The United Kingdom passes a genuinely radical generational ban on smoking; the US Senate unanimously bans members and staffers from betting on prediction markets, after some were caught betting on their own races; and Meta inks a deal to beam solar power down from space.What Could Go Right? is produced by The Progress Network and Kaleidoscope.For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.orgSubscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/Watch the podcast on YouTube: / theprogressnetworkFollow us on X, Instagram, Facebook, TikTok: @progressntwrkFollow Emma on Instagram: https://www.instagram.com/heyemmavarv/
- 1 weeks ago36 min
Why $6 Gas Isn't the End of the World | with Jason Bordoff
What happens when the global energy supply faces its greatest disruption since the 1970s? Jason Bordoff, a leading energy expert and former advisor in the Obama White House, joins host Zachary Karabell to navigate a world where the Strait of Hormuz is closed and gasoline prices are soaring. The conversation moves past the immediate panic at the pump to look at the future of how we power our lives. Bordoff shares personal stories of his father’s Brooklyn gas station in the 1970s, contrasting that era with today's physical reality of the shale revolution. The discussion focuses heavily on the innovation frontier. Bordoff and Karabell explore whether new technologies like advanced geothermal, modular nuclear power, and even fusion can finally deliver on the promise of universal energy abundance. While acknowledging the hard truths of climate change and the energy needs of emerging markets, Bordoff explains why he is betting on policy and technology over pessimism. What Could Go Right? is produced by The Progress Network and Kaleidoscope. For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.org Subscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/ Watch the podcast on YouTube: / theprogressnetwork Follow us on X, Instagram, Facebook, TikTok: @progressntwrk Subscribe to Zachary’s Substack: www.edgyoptimist.substack.com/
- 2 weeks ago13 min
Chernobyl’s Unintended Nature Reserve + The End of the Coal Era and a New Frontier in IVF
For the first time in over a century, renewables have knocked coal out of the top spot for global electricity generation — and solar is the reason why. Emma Varvaloucas, Executive Director of The Progress Network, breaks down what this energy milestone actually means, and why geopolitics is unexpectedly accelerating the clean energy transition. Plus: forty years after the worst nuclear disaster in history, wildlife is flourishing inside the Chernobyl exclusion zone; a Utah startup claims it has grown functional human sperm in a lab — a potential breakthrough for male infertility; and NASA is branching into the human organ delivery industry. What Could Go Right? is produced by The Progress Network and Kaleidoscope. For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.org Subscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/ Watch the podcast on YouTube: / theprogressnetwork Follow us on X, Instagram, Facebook, TikTok: @progressntwrk Follow Emma on Instagram: https://www.instagram.com/heyemmavarv/
- 2 weeks ago42 min
Can We Achieve "Super Abundance" Without AI Doom? | with Sebastian Mallaby
What happens when the person building the world's most powerful technology is just as worried about it as we are? Sebastian Mallaby, the Pulitzer Prize-nominated author of The Infinity Machine, joins host Zachary Karabell to pull back the curtain on Demis Hassabis, the founder of DeepMind who is currently leading the global charge into artificial intelligence. From the "Ender’s Game" mission that drives Hassabis to the chilling logic of why machines might accidentally develop a "survival instinct," this episode explores the mindset of the people shaping our future. Mallaby and Karabell discuss the "infinity" of data required to make these systems work and why the massive hunger for compute power is reshaping the global economy in real-time . Drawing a haunting parallel to Alan Greenspan and the 2008 financial crisis, Mallaby asks a difficult question: Can "the man who knew" the risks actually prevent the catastrophe he sees coming?. Together, they navigate the tension between pure scientific discovery and cutthroat Silicon Valley competition, the potential for a "Nuclear Non-Proliferation" style agreement with China, and the hidden dangers of the "open vs. closed" model debate.What Could Go Right? is produced by The Progress Network and Kaleidoscope.For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.orgSubscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/Watch the podcast on YouTube: / theprogressnetworkFollow us on X, Instagram, Facebook, TikTok: @progressntwrkSubscribe to Zachary’s Substack: www.edgyoptimist.substack.com/Follow him LinkedIn: www.linkedin.com/in/zacharykarabell
- 3 weeks ago11 min
Trump’s Surprising Move on Psychedelics + A Record Year for Humpback Whales
Trump just signed an executive order to fast-track psychedelic medical research. Emma Varvaloucas, the Executive Director of The Progress Network, breaks down how a 50-year political taboo went mainstream. Plus: San Diego achieves water independence and starts brewing beer from recycled sewage, a humpback whale stampede breaks a sighting record off South Africa, and gene-edited bananas that don't turn brown are finally here.What Could Go Right? is produced by The Progress Network and Kaleidoscope.For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.orgSubscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/Watch the podcast on YouTube: / theprogressnetworkFollow us on X, Instagram, Facebook, TikTok: @progressntwrkFollow Emma on Instagram: https://www.instagram.com/heyemmavarv/
- 3 weeks ago40 min
Is the World Order Actually Disintegrating? | with Ian Bremmer
What happens when the rules of the global game are being rewritten in real-time? Ian Bremmer, the founder of Eurasia Group and GZERO Media, joins host Zachary Karabell to discuss how to navigate a world defined by a "long geopolitical recession" and the erosion of the post-1945 order. From the escalating conflicts in the Middle East and the surprising vulnerabilities of the economic models in the Gulf to the "asymmetric war fighting" that allows drones to bring the global economy to its knees, this episode reckons with a world that seems to be disintegrating rather than coming together. Bremmer and Karabell explore why we aren’t getting a better picture of what’s happening on the ground in places like Iran and Yemen, and whether the "noise" of modern social media is a tool for freedom or a new mechanism for state control. As political revolutionaries rise and established media organizations downsize, Bremmer and Karabell ask: is our current information environment worse than it was 30 years ago, or can individuals still "sniff out" the truth? And: Is this the peak of global chaos, or just a cyclical trough before a new rebound? What Could Go Right? is produced by The Progress Network and Kaleidoscope. For transcripts, to join the newsletter, and for more information, visit: theprogressnetwork.org Subscribe to our (FREE) Substack newsletter: https://theprogressnetwork.org/newsletter/ Watch the podcast on YouTube: / theprogressnetwork Follow us on X, Instagram, Facebook, TikTok: @progressntwrk Subscribe to Zachary’s Substack: www.edgyoptimist.substack.com/ Follow him LinkedIn: www.linkedin.com/in/zacharykarabell Follow Zachary on X @zacharykarabell
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About What Could Go Right?
What if instead of being on the brink of disaster, we’re on the cusp of a better world? No one can deny the challenges the world faces, from pandemics to climate change to authoritarianism. But pessimism and despair are too easy a response. Each week, Progress Network Founder Zachary Karabell and Executive Director Emma Varvaloucas convene a diverse panel of experts to discuss the central issues of our era, including sustainability, polarization, work, and the economy, and make the case for a brighter future. They emerge from their conversations with a counterintuitive but informed take: progress is on its way.
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