Reflections on Proteomics - 2025 Yea-End Wrap-Up

On this episode of Translating Proteomics, Parag and Andreas share their reflections on proteomics developments in 2025 largely inspired by their observations at the World HUPO 2025 conference in Toronto. Whether you agree, disagree, or simply want to share some of your own observations on proteomics, please post your thoughts in the comments.We look forward to even more exciting developments in 2026!Chapters00:00 - 00:35 – Intro00:36 – 07:00 - Increased focus on applications of proteomics and less on method developmentLearn more about One Health from our conversation with Professor Jennifer Geddes-McAlisterhttps://youtu.be/JFwvTdkb5bw07:01 – 12:47 - Increase in people talking about the importance of proteoformsLearn more about proteoforms in our episode featuring proteoform pioneer Professor Neil Kelleherhttps://youtu.be/3pPuxVrMxpw12:47 – 17:26 - An increase in multiomics studies17:27 – 20:03 - A shift to larger scale proteomics studiesFor a great example of a multi-platform comparison study, check out Kirsher et al., 2025https://www.nature.com/articles/s42004-025-01665-120:03 – 25:07 - Increased integration of AI into proteomics workflowsFor an example of how proteomics workflows can be modified with multiomic data, check out Suhre et al., 2025https://www.nature.com/articles/s41588-025-02413-w25:08 – 30:05 – Recognition of the need to assess quality across proteomics workflows30:06 – 32:19 – Less of a focus on spatial proteomics this year than in past years32:20 – 35: 13 - Parag and Andreas share their predictions for 202635:14 – End – Outro