The Human Upgrade: Biohacking for Longevity & Performance

Ozempic Hair, GLP-1 Kids, Gut-Brain Anxiety, Food Additives, Taurine, and more : 1544

September 25, 2026·14 min
Episode Description from the Publisher

Novo Nordisk Eyes Hair-Loss Market in Consumer-Health Expansion Novo Nordisk, the company behind Ozempic and Wegovy, is exploring hair loss as one of several possible areas for future expansion, alongside menopause and addiction. The company has not announced a hair-loss drug, clinical trial, acquisition, or partnership, but Chief Scientific Officer Martin Holst Lange pointed to the category during the company's 2026 Capital Markets Day. Host Dave Asprey breaks down why hair loss makes strategic sense for a company already deeply involved in endocrine biology, how emerging treatments are moving beyond traditional options like minoxidil and finasteride, and why sudden shedding during rapid GLP-1 weight loss may be telogen effluvium rather than traditional pattern baldness. Sources: https://www.bloomberg.com/news/articles/2026-09-22/ozempic-maker-novo-looks-to-target-hair-loss-in-consumer-push https://www.novonordisk.com/investors/capital-markets-day-2026.html https://www.irishexaminer.com/business/companies/arid-41914219.html ~~~Nearly One in Six Pediatric GLP-1 Users Diagnosed With a Nutritional Deficiency A study of 2,031 children and adolescents ages 10 to 17 who were prescribed GLP-1 receptor agonists found that 16.88% received a new diagnosis related to a nutritional deficiency within one year. Vitamin D deficiency was the most common, appearing in about 12.4% of the group, while smaller numbers were diagnosed with nutritional anemia or iron deficiency anemia. Host Dave Asprey explains why the study does not prove GLP-1 drugs caused these deficiencies, but highlights a bigger concern: only about 5% of the children had documented nutrition counseling within the first 30 days, even though appetite suppression during adolescence can reduce intake of protein, iron, calcium, vitamin D, B vitamins, and other nutrients needed for growth. Sources: https://doi.org/10.1177/21532176261486979 https://www.sciencedaily.com/releases/2026/09/260923035926.htm https://pharmaceutical-journal.com/article/news/children-taking-glp-1s-can-be-at-risk-of-nutritional-deficiencies-study-finds ~~~Stronger Stomach-Brain Synchrony Associated With Poorer Mental Health Researchers studying the electrical rhythm of the stomach alongside brain activity found an unexpected relationship: stronger synchronization between gastric signals and certain brain networks was associated with worse mental health measures, including higher anxiety, depression, stress, and fatigue. The strongest associations appeared in networks involved in attention and cognitive control. Host Dave Asprey explains why the findings do not prove stomach-brain synchronization causes mental health problems, but expand the gut-brain conversation beyond the microbiome to include electrical activity, neural signaling, hormones, immune pathways, and metabolites. Sources: https://www.nature.com/articles/s44220-025-00468-6 https://health.au.dk/en/display/artikel/the-stomachs-brain-is-more-in-sync-with-the-mind-during-mental-distress https://medicalxpress.com/news/2025-08-stomach-brain-sync-mind-mental.html ~~~Food Preservatives and Additive Mixtures Associated With Cardiovascular Risk A large French NutriNet-Santé study involving more than 112,000 adults found that higher exposure to total preservatives was associated with a higher incidence of hypertension, while several individual additives were also linked to elevated risk. A newer September 2026 analysis from the same cohort examined combination

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