Why Removing Amyloid From the Brain Isn't Enough to Stop Alzheimer's with Dr. Jonathan Fellows | E220

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Thank you to our sponsors:EVY - https://www.optoceutics.com/perlmutter and the code perlmutter26 will be auto-applied to your order to get $200 off &amp; free shipping (90 days risk-free). 3x4 Genetics - https://3x4genetics.com/DrPerlmutterfor a special offer when you sign up to decode your genetics and get personalized, science-backed health recommendations. ====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your copy today at https://www.braindefenders.com. ====What if the gene you&#39;ve been told to fear isn&#39;t actually a verdict on your future, and the disease you&#39;re racing to treat has already been silently progressing for two to three decades before anyone notices? In this episode, Dr. Jonathan Fellows joins me to challenge how we think about Alzheimer&#39;s risk, diagnosis, and treatment, making the case that early detection and lifestyle intervention matter more than the medications most people pin their hope on.Dr. Jonathan Fellows is a neurologist with more than 25 years of clinical experience and serves as the Director of the Alzheimer&#39;s Disease and Memory Disorder Center at the Michigan Institute for Neurological Disorders, part of Corewell Health in Farmington Hills, Michigan, the largest private practice neurology group in the state. 00:00 - Introduction00:39 - Brain Defenders: A New Way to Think About Brain Health02:59 - Welcoming Dr. Jonathan Fellows03:51 - Why Neurology School Doesn&#39;t Teach Prevention05:27 - Inside the Michigan Institute for Neurological Disorders07:44 - Starting the Conversation When a Family Gets the Alzheimer&#39;s Diagnosis08:00 - Apraxia and the Real Warning Signs of Cognitive Decline09:00 - Why Amyloid Alone Doesn&#39;t Equal an Alzheimer&#39;s Diagnosis09:55 - The Centiloid Score: Measuring Amyloid in the Brain11:21 - Blood-Based Biomarkers and the Rise of P-tau 21713:19 - Elevated P-tau 217 at 40: A Wake-Up Call You Can&#39;t Ignore13:32 - Habits in Your 30s and 40s vs. Disease in Your 60s and 70s16:53 - 40 Hz Light Therapy and Cognitive Decline18:53 - Why Not Every Amyloid-Positive Patient Should Get Anti-Amyloid Drugs21:00 - Alzheimer&#39;s Drug Therapy Today vs. Where MS Treatment Stood in the 90s23:59 - Why Early and Presymptomatic Detection Matters25:21 - Will Anti-Amyloid Drugs Be Pushed to Presymptomatic Patients?25:39 - What We Know for a Fact About Lifestyle and Disease Progression26:27 - A Real Patient Case: When to Say No to Anti-Amyloid Drugs<a h