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Run Long Run Healthy

The Hidden Role The Brain Plays In Running and Recovery (New Research)

March 6, 2026·23 min
Episode Description from the Publisher

Brady explains a new study that looks at the effect that endurance exercise has on the brain, both during and after exercise - and the potential implications for how runners should think about the post-run window.00:00 The brain’s role in running02:00 Describing the study: measuring brain activity during05:40 findings: What happens in the brain during and after exercise13:10 ProBio Nutrition (ad)14:29 Does this work in humans? And neurodoping16:05 Takeaways for runners: allow a window for recovery20:18 Can we hack the brain? Brady’s article on the discussion:How Exercise Hardwires the Brain for Endurancehttps://www.physiologicallyspeaking.com/p/physiology-friday-306-how-exerciseThe study:Exercise-induced activation of ventromedial hypothalamic steroidogenic factor-1 neurons mediates improvements in endurancehttps://pubmed.ncbi.nlm.nih.gov/41687612/Run Long Run Healthy is brought to you by Marathon Handbook.➡ https://marathonhandbook.comSubscribe to the Run Long Run Healthy podcast:➡ Spotify: https://bit.ly/RLRH-spotify➡ Apple podcasts: apple.co/43iqUKxGet the RLRH weekly newsletter (choose free or paid):➡ https://marathonhandbook.com/run-long...➡ https://runlongrunhealthy.substack.com/Follow us online:BRADY ON X ➡ https://x.com/B_Holmer/PHYSIOLOGICALLY SPEAKING (Brady's Newsletter)  ➡ https://www.physiologicallyspeaking.com/MARATHON HANDBOOK IG ➡   / marathon.handbook

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