天方烨谈

脑膜瘤复发,为什么偏偏需要BNCT?

November 3, 2026·2 min
Episode Description from the Publisher

脑膜瘤复发,难处是“不敢再照”,而非“切不切”。它偏好长在颅底、海绵窦、矢状窦旁,手术像在雷区里挖树根,切不干净;而放疗的剂量额度往往第一次就用掉大半,视神经、脑干、垂体、颅神经都经不起二次叠加。BNCT 处理的就是这道难题。含硼药物经氨基酸转运体选择性钻进肿瘤细胞,中子一照触发核反应,放出的 α 粒子和锂离子射程只有一个细胞直径,杀伤发生在细胞内部,边界几乎就是细胞边界。

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