Perform with Dr. Andy Galpin

Female Training, Hormones & Nutrition: Fact vs. Fiction | Dr. Lauren Colenso-Semple

June 10, 2026·2h 8m
Episode Description from the Publisher

In this episode, I sit down with Dr. Lauren Colenso-Semple to examine what the science says about female-specific training and nutrition. We discuss why so little research has historically focused on women, what makes menstrual cycle research so difficult and expensive to run, and what her own dissertation found when she measured muscle protein synthesis across cycle phases. Dr. Colenso-Semple explains the real hormone fluctuations of the menstrual cycle, why testosterone matters far less for women's muscle than people assume, and why men and women gain strength and size at the same relative rate at any age, including through menopause. We also cover low energy availability, scientific literacy, and how to figure out what works for you. This episode is for anyone, coach or lifter, trying to separate evidence from misinformation in women's fitness. Sponsors Momentous: https://livemomentous.com/perform David: https://davidprotein.com/perform TrueMed: https://truemed.com/perform Eight Sleep: https://eightsleep.com/perform Chapters (00:00:00) Lauren Colenso-Semple (00:01:51) The Lit Review That Never Was (00:07:01) Why Women Got Bad Training Advice (00:11:23) Individualization & Where Sex Actually Ranks (00:21:09) Estrogen, Rodent Models & the Anabolic Myth (00:34:52) Hormones Across the Menstrual Cycle (00:45:18) The Myth of the Textbook 28-Day Cycle (00:51:41) Why Female Research Is So Hard (00:57:55) Inside Lauren's Dissertation: Tracers & Biopsies (01:06:10) Strength, Power & Hypertrophy: No Phase Effect (01:14:13) The Real Role of Testosterone & Menopause (01:23:36) Becoming a Better Consumer of Science (01:50:10) Low Energy Availability & RED-S (01:57:30) Advice for the Average Woman Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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