
The full quad is back and we're getting right into the tech drama: AI backlash (from Reese Witherspoon to everyday skepticism), breakthrough science like CRISPR entering its “it actually works” era, and major power shifts across tech — from Apple succession chatter to Jensen Huang’s leadership moments and the brewing battle between OpenAI and Elon Musk. They squad digs into SpaceX IPO dynamics, the rise of “traces” data as the next AI battleground, and what happens when AI gives more people the power to build. Chapters:0:17 — Welcome Back: Full Quad Edition1:07 — Creatine, AI Stuffies, and the Opening Chaos4:37 — Breakthrough Prize & CRISPR Finally Working5:47 — One-of-One Gene Therapy Becomes Real7:07 — The AI Backlash Is Real8:47 — UBI vs. Meaning: The Real Debate10:57 — Jensen’s “I Didn’t Wake Up a Loser Today” Moment12:47 — Apple Succession: Tim Cook → John Ternus16:17 — Asset Prices vs. Reality21:17 — Elon vs. OpenAI: The Trial27:07 — SpaceX IPO: Biggest in History?29:27 — xAI, Cursor, and the $60B Bet36:07 — Traces Data: The Next AI Battleground40:07 — Workplace Surveillance & Employee Data48:27 — Who Gets to Build? (6B Users vs. 50M Builders)51:07 — AI: Equalizer or Concentrator?We’re also on ↓X: https://twitter.com/moreorlesspodInstagram: https://instagram.com/moreorlessYouTube: https://youtu.be/bjePLXg64n0Connect with us here:1) Sam Lessin: https://x.com/lessin2) Dave Morin: https://x.com/davemorin3) Jessica Lessin: https://x.com/Jessicalessin4) Brit Morin: https://x.com/brit
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