JAMA Clinical Reviews

An Overview of Postural Orthostatic Tachycardia Syndrome (POTS)

August 24, 2026·28 min
Episode Description from the Publisher

POTS is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. Author Satish Raj, MD, MSCI, of University of Calgary Cumming School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss current evidence about the pathophysiology, diagnosis, and management of POTS. Related Content: Postural Orthostatic Tachycardia Syndrome (POTS)

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