Innovating Clinical Trials

Ep 2.29: Lasagna's Law and Building Recruitment Forecasts You Can Actually Trust

July 10, 2026·18 min
Episode Description from the Publisher

Every trial starts with a number on a slide, patients needed, months allotted, a clean straight line on a chart. Liam and Ted pull that line apart in this episode, starting with Lasagna's Law: the 1970s observation that eligible patients seem to vanish the moment a trial opens and reappear the moment it closes. They dig into why recruitment forecasts go wrong not because the math is bad, but because the assumptions underneath the math are never tested, tracked, or even written do...

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