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Innovating Clinical Trials: Daily Summaries Delivered
by Liam Eves and Ted Trafford
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. With 30 years of experience in clinical research, Ted serves as the Director of Business Development, driving business growth and leading Feasibility and Site Relationship teams at Probity Medical Research, a clinical trial site administrative support company with a consortium of 75+ sites across four countries. As a writer and speaker, Ted contributes to thought leadership and strategic initiatives in the clinical trials industry, leveraging his extensive experience and creative approach to drive meaningful discussion and progress for Sponsors, CROs, Sites and Technology Vendors. Liam's held executive roles in SMOs and CROs, and led all major functions of trial delivery. His journey into the field began unexpectedly after an injury ended his career as a professional footballer. Over the years Liam has optimized trial delivery methods / systems for effective enrollment and trial delivery. Currently, he focuses on building and advising companies in the clinical trial space. Opinions expressed are those of the participants and not their employers.
Latest Episodes
The most recent episodes — sign up to get AI-powered summaries of each one.
- Yesterday18 min
ICT Ep 2.41: Robert Goldman on "Optimism Is Not an Enrollment Plan" (Part 1/3)
In Part 1 of this three-part conversation, Liam and Ted sit down with Robert Goldman, Vice President and Global Head of Clinical Operations at Contraline, who brings nearly 20 years of clinical research experience spanning CRO roles and sponsor-side clinical operations, to talk about why the industry rewards optimism in planning and demands realism in execution. Robert shares how a detour through Caribbean medical school led him into clinical research by accident, and what he has learned abo...
- 1 weeks ago17 min
ICT Ep 2.40: Duncan Shaw on the AI Translation Trap: Why the Human “Last Mile” Still Matters When the Stakes Are High (Part 3/3)
In Part 3 of this three-part conversation, Liam and Ted wrap up their discussion with Duncan, President at DTS Language Services about AI, risk mitigation, and the human factors that are hard to capture in clinical trial translation. Duncan calls translation the “last mile” of clinical trials, where small details can decide whether a site activates or a patient stays in a study. He explains why AI has a place when millions of words are on tight timelines, but argues that low-volume, high-ris...
- 1 weeks ago16 min
ICT Ep 2.39: Duncan Shaw on the Translation “Quilt Factor”: How Inconsistency Can Erode Patient Trust and Derail Trial Operations (Part 2/3)
In Part 2 of this three-part conversation, Liam and Ted continue their discussion with Duncan, President at DTS Language Services about patient trust, consistency, and the operational realities of translating clinical trial content. Duncan explains how small issues, from inconsistent terminology to differences in date formats, can undermine a patient’s confidence in a study and even lead to missed visits. Trust comes from consistency, fewer handoffs, and an approach that fits the purpo...
- 1 weeks ago15 min
ICT Ep 2.38: Duncan Shaw on the Hidden Risks of Clinical Trial Translation: What Happens With One Wrong Word (Part 1/3)
In Part 1 of this three-part conversation, Liam and Ted sit down with Duncan, President at DTS Language Services, to talk about the good, the bad, and the ugly of clinical trial translation. Drawing on experience in both pharmaceutical and language services, Duncan explains why translation is far more than converting words from one language to another, and why a mistranslation in a clinical study isn’t just a typo but a potential risk to a patient, a trial, or a regulatory submission. Duncan...
- 1 weeks ago18 min
ICT Ep 2.37: "You Lose a Patient You Didn't Even Know You Lost" Why No One Owns Recruitment
In this episode, Ted introduces the “ENROLL Corporation” (Everyone Needed for Recruitment Optimization Leadership and Logistics) an imaginary joint venture owned by the sponsor, the CRO, every site, and every vendor. He explains why most recruitment providers solve one small piece of the problem, much like a wildlife photographer so focused through a 500mm lens that an animal wanders past unnoticed. Liam adds a river analogy about who “eats their own cooking,” and together they look at ...
- 1 weeks ago16 min
ICT Ep 2.36: Robin Piazza on ICH E6 R3 and the New Rules for Safety Oversight (Part 2/2)
In Part 2, Robin Piazza, Liam and Ted get specific about what good safety oversight actually looks like in practice, and what sponsors are getting wrong under the shift from FDA 2024 guidance to the stricter ICH E6 R3 standard. We explore: - FDA 2024 guidance vs. ICH E6 R3: why global studies need one uniform plan - Why a DMC charter is a “how the DMC will operate," not evidence, and is what inspectors actually want to see, and whether the charter was followed. - The hidden conf...
- 2 weeks ago20 min
ICT Ep 2.35: Robin Piazza on the Safety Oversight Gap No One's Training For (Part 1/2)
Robin Piazza reached out to us directly with this topic suggestion, and we’re glad she did. In Part 1 of this two-part conversation, Liam and Ted sit down with Robin, Founder of Sapiens GC, who spent over 20 years building and running the industry’s first commercial data monitoring committee service before going independent. She breaks down what a data safety monitoring committee actually does, where sponsors, CROs, and vendors each fall short, and why having one independent, unblinded party ...
- 2 weeks ago15 min
ICT Ep 2.34: Study Startup Delays Are a Symptom: What Happens When You Stop and Listen
In this episode, Liam and Ted ask a simple “what if”, what if the industry took the time to really listen? Ted starts with a study startup delay that looks like a tooling problem but turns out to be a relationship problem. While Liam shares what happened when he pulled a frontline team member into a leadership meeting and found a patient-flow blocker that had backed up a 120-patient-a-day site for days. They talk about why most trial meetings leave no room for problem-solving or relat...
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About Innovating Clinical Trials
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. With 30 years of experience in clinical research, Ted serves as the Director of Business Development, driving business growth and leading Feasibility and Site Relationship teams at Probity Medical Research, a clinical trial site administrative support company with a consortium of 75+ sites across four countries. As a writer and speaker, Ted contributes to thought leadership and strategic initiatives in the clinical trials industry, leveraging his extensive experience and creative approach to drive meaningful discussion and progress for Sponsors, CROs, Sites and Technology Vendors. Liam's held executive roles in SMOs and CROs, and led all major functions of trial delivery. His journey into the field began unexpectedly after an injury ended his career as a professional footballer. Over the years Liam has optimized trial delivery methods / systems for effective enrollment and trial delivery. Currently, he focuses on building and advising companies in the clinical trial space. Opinions expressed are those of the participants and not their employers.
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