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First Principles of Medicine: Daily Summaries Delivered
by 1PM
Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles. When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.
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- 5 days ago43 min
#39B Abnormal Uterine Bleeding (Part II)
First Principles of Abnormal Uterine Bleeding (AUB)In this episode, we're going to break it all down from first principles. We'll walk through how to take a focused history without getting lost in the menstrual timeline, what investigations actually matter (and which ones don't), and how management changes depending on what's causing the bleeding.As always, this isn't about memorising endless lists. It's about understanding the why behind the questions you ask and the tests you order, so the next time you're on ward rounds or in an OSCE, you'll know exactly where to start.So grab your coffee, your notebook, or your favourite study snack, and let's dive into abnormal uterine bleeding—because periods might be monthly, but OSCEs can ask about them any day of the year!Disclaimer: This episode was recorded on 8 May 2026. At the time of recording, the condition now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) was referred to as Polycystic Ovary Syndrome (PCOS). Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.
- Jun 13, 202629 min
#39 Abnormal Uterine Bleeding (Part I)
First Principles of Abnormal Uterine Bleeding (AUB)Think it's "just PMS"? Think again! In Part I of our AUB series, we dive into what counts as normal menstrual bleeding, when bleeding becomes abnormal, and the common causes behind it. Join us as we unpack the basics of Abnormal Uterine Bleeding and turn a confusing topic into something clear, practical, and surprisingly fascinating.Disclaimer: This episode was recorded on 1 May 2026. At the time of recording, the condition now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) was referred to as Polycystic Ovary Syndrome (PCOS). Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.
- Nov 8, 20254 min
#38B - Seizures...in 5 minutes!
The First Principles of Seizures (Summary): Join us for the summary version of our seizures episode.1PM Notion: Seizures=== Other Links ===1PM WebsiteCheck out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded 27th of July, 2025. Hosts: Benjamin Earner, Saud Rana, Jasper Jackson. Produced by Benjamin Earner.If you have any ideas or feedback, comment on this Notion document, or shoot us an email at hello@1pm.wiki© First Principles of Medicine 2025
- Nov 8, 202558 min
#38A - Seizures: When electricity becomes pathology!
The First Principles of Seizure: Join us as we explore the electrifying world of seizures and epilepsy. We hope this episode will provide you with a clearer framework to describe, investigate, diagnose, and manage seizures from a patient’s first seizure to the emergency of status epilepticus.1PM Notion: Seizures=== Other Links ===1PM WebsiteCheck out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded 27th of July, 2025. Hosts: Benjamin Earner, Saud Rana, Jasper Jackson. Produced by Benjamin Earner.If you have any ideas or feedback, comment on this Notion document, or shoot us an email at hello@1pm.wiki© First Principles of Medicine 2025
- Sep 2, 20257 min
#37B - The Limping Child... in 7 minutes!
The First Principles of The Limping ChildSummary version of "The Limping Child," best used as brief revision of key concepts explored in the original episode.=== Other Links ===Check out our notion document on this topic:https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a86b736Check out our website 1pm .wiki for the Notion document, free Anki flashcards, and podcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded May 2025. Hosts: Abdulla Ellagta, Norman Luyt, Danial KhongProduced by Abdulla EllagtaIf you have any ideas or feedback, comment on the Notion document, or shoot us an email at hello@1pm.wiki© First Principles of Medicine 2025
- Sep 1, 202536 min
#37A - The Limping Child
The First Principles of The Limping ChildIn this episode we seek to break down a common paediatric presentation into the essentials, primarily covering a systematic approach to differentiating the causative pathologies. Join us as we limp towards a diagnosis.=== Other Links ===Check out our notion document on this topic:https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a86b736 Check out our website 1pm .wiki for the Notion document, free Anki flashcards, and podcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded May 2025. Hosts: Abdulla Ellagta, Norman Luyt, Danial KhongProduced by Abdulla EllagtaIf you have any ideas or feedback, comment on this Notion document, or shoot us an email at hello@1pm.wiki© First Principles of Medicine 2025
- Aug 11, 20254 min
#36B - Osteoporosis... in 4 minutes!
The First Principles of osteoporosis: Join us for the summary version of this episode for a quick run down on the presentation, diagnosis and management of osteoporosis. === Other Links ===1PM Websitehttps://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_linkCheck out our new website 1pm .wiki for the Notion document, free Anki flashcards, andpodcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded May 2025. Hosts: Norman Luyt, Elliott Willis, Danial KhongProduced by Norman Luyt.If you have any ideas or feedback, comment on this Notion document, or shoot us an emailat hello@1pm.wiki© First Principles of Medicine 2025
- Aug 11, 202536 min
#36A - Osteoporosis: Falls, Fractures and Frailty.
The First Principles of osteoporosis: Join us as we discuss the pathophysiology, diagnosis and management of osteoporosis, a common condition which you will encounter throughout your medical career. === Other Links ===1PM Websitehttps://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_linkCheck out our new website 1pm .wiki for the Notion document, free Anki flashcards, andpodcast episodes.Instagram: https://www.instagram.com/firstprinciplesofmedicine/Recorded May 2025. Hosts: Norman Luyt, Elliott Willis, Danial KhongProduced by Norman Luyt.If you have any ideas or feedback, comment on this Notion document, or shoot us an emailat hello@1pm.wiki© First Principles of Medicine 2025
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About First Principles of Medicine
Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles. When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.
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