Fat Science

Mailbag: When Weight Loss Stalls on GLP-1s

July 6, 2026·45 min
Episode Description from the Publisher

Is it normal for GLP-1 medications to become less effective over time?Dr. Emily Cooper discusses listener questions about the nuances of metabolic health and the real reasons behind weight fluctuations and food cravings. With insights into GLP-1 medications, mechanical eating, and more, the episode aims to debunk myths and provide science-based encouragement.KEY TAKEAWAYSTrusting your body's hunger signals can prevent metabolic slowdown.Mechanical eating can help manage sugar cravings and maintain metabolic health.Navigating pediatric metabolic issues requires understanding genetic influences and appropriate medical intervention.NOTABLE QUOTE"It's not your fault. Trust your body and step up to the higher end of your metabolic flexibility." — Dr. Emily Cooper LINKS & RESOURCESAmerican Board of Obesity Medicine: obesitymedicine.org Links & ResourcesPodcast Home: fatsciencepodcast.comCooper Center for Metabolism: coopermetabolic.comResources from Dr. Cooper: coopermetabolic.com/resourcesJoin Our Community: patreon.com/cw/FatSciencePodcastSubmit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comFat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

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