Dr. Joseph Mercola - Take Control of Your Health

Why We Started with Your Gut

July 21, 2026·6 min
Episode Description from the Publisher

Story at-a-glance Butyrate is a short-chain fatty acid that serves as the primary fuel for the cells lining your colon. These cells rely on it for the majority of their energy, making it one of the most important molecules for gut health Your gut bacteria produce butyrate by fermenting fiber, but modern diets and disrupted microbiomes mean many people make too little, and the gut suffers for it Conventional butyrate supplements are largely absorbed high in the digestive tract and destroyed before reaching the colon, where the molecule does its most important work — a textbook delivery failure That combination — deep, well-documented benefit plus near-total delivery failure — makes butyrate the ideal proving ground for targeted delivery technology It is the reason we chose the gut as the first demonstration of what 22nd Century delivery can do, and why more than 35,000 people are already waiting for what comes next

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