Diabetic Foot Files

Forgotten Infection Friday: The Hidden Danger of Pyomyositis

September 18, 2026·22 min
Episode Description from the Publisher

Dr. G discusses pyomyositis — a deep skeletal muscle infection that can occur in people with diabetes, how it differs from cellulitis, its stages, common causes, typical pathogens, diagnostic steps including MRI and labs, and the importance of source control, imaging, and vascular assessment. Key takeaways: the visible ulcer may be only the surface of a deeper infection, early recognition and imaging are critical, and management often requires both antibiotics and surgical drainage plus attention to offloading and vascular status.

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