Episode 132: The Reality of Being a CEO – Leadership Lessons from the Front Lines of Biotech

What does it really mean to be a CEO, and why does the role feel so different once you’re in the seat? In this episode, Elaine Hamm, PhD, sits down with James Zanewicz, JD, LLM, RTTP, CEO of Connect, to unpack the realities of leadership at the highest level. James shares what surprised him most about becoming a CEO, the weight of responsibility, and how his perspective on leadership has evolved since stepping into the role. Together, they explore the evolving nature of leadership, the importance of building the right team, and why being a CEO is less about control and more about empowerment. Whether you’re a founder, aspiring executive, or already in the role, this episode offers a grounded look at what it truly takes to succeed as a CEO. In this episode, you’ll learn: Why being a CEO can feel isolating, and how to build the right support system. How to navigate decision-making, prioritization, and uncertainty when the stakes are high. The importance of team building, self-awareness, and continuous learning in effective leadership. Tune in to hear real-world CEO insights and learn how to lead with clarity, resilience, and purpose in today’s biotech landscape. Links: Connect with James Zanewicz, JD, LLM, RTTP, and learn about Connect. Connect with Elaine Hamm, PhD, and learn about Tulane Medicine Business Development and the School of Medicine. Connect with Gretel von Son, MBA, Tre Braquet, Petra Stegmann, PhD, Lizbeth Dargi, Daniela Gama, and Rick Valencia. Learn more about OnWard. Check out the books The First 90 Days, The New CEO, and The Five Dysfunctions of a Team. Check out our previous episode on Board Composition. Connect with Ian McLachlan, BIO from the BAYOU producer. Learn more about BIO from the BAYOU - the podcast. Bio from the Bayou is a podcast that explores biotech innovation, business development, and healthcare outcomes in New Orleans & The Gulf South, connecting biotech companies, investors, and key opinion leaders to advance medicine, technology, and startup opportunities in the region.