All in the Mind

Could a keto diet help treat bipolar depression?

June 9, 2026·28 min
Episode Description from the Publisher

Claudia Hammond explores intriguing early evidence that a ketogenic diet - high fat, low carbs - might help treat bipolar depression.We already know this diet can help with some kinds of epilepsy. But now, after a promising pilot study, the Wellcome trust is funding a £7.9 million trial to look at whether it could also help reduce depression in people living with bipolar disorder. Professor Daniel Smith and research fellow Dr Iain Campbell from the University of Edinburgh, take us into the emerging field of ‘metabolic psychiatry’. Also in the programme, Professor Nilli Lavie of UCL reveals what happens to our brain’s grey matter as we try to stay focused in an age of constant distraction. As information and entertainment are always within reach, her research asks how these shifting habits may be reshaping our attention - and our brains.And Professor Daryl O’Connor discusses emerging research into the hormone oxytocin and its surprising role in wound healing, as well as new insights into how cultural experiences might help slow the ageing process.Presenter: Claudia Hammond Producer: Pamela Rutherford Studio Manager: Tim Heffer Production Coordinator: Jana Bennett-Holesworth Content Editor: Ilan Goodman

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