Weight and Healthcare

Does Weight-Cycling Cause Loss of Muscle Mass?

September 2, 2026·5 min
Episode Description from the Publisher

Reader Barbara recently brought the study “Association of Weight Cycling with MRI-Based Thigh Muscle Quality and Knee-Adjacent Ob*sity” to my attention.The study sought to determine if repeated weight gain and loss (also known as weight cycling or yo-yo dieting) was associated with sarcopenia which they explain is defined as a loss of muscle strength and muscle mass and a decline in physical performance. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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