📅 ThursdAI - Apr 30 - DeepSeek V4 (1.6T MoE), Cursor SDK Wins WolfBench, Mayo's REDMOD Saves Lives, Stripe Gives Agents a Wallet & more

Hey everyone, Alex here 👋Tomorrow is May. May! I genuinely cannot believe we’re four months into 2026 already, and the AI news cycle is showing zero signs of slowing down. This week’s show was a wild one! We opened with what is genuinely one of the most important AI stories I’ve ever covered (Mayo Clinic AI detecting pancreatic cancer THREE YEARS before human radiologists), we covered the return of the Chinese whale with DeepSeek V4, OpenAI got caught in their own system prompt begging GPT-5.5 to please stop talking about goblins, and I literally gave my coding agent a credit card and asked it to buy my fiancée a wedding gift with the new Strip Link skill and CLI! Oh yeah, I’m getting married next Tuesday! 💍 So next week’s show will be a little different. I’ll be back the week after to catch you up on whatever drops in my absence (almost certainly something major, knowing this industry).Lots to get through, so let’s dive in. (also, in the end I have a full month recap of every major launch, don’t miss) ThursdAI - Highest signal weekly AI news show is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.Mayo Clinic’s REDMOD: AI Detects Pancreatic Cancer 3 Years Early 🔥 (X, Blog, Announcement)I know we usually cover Models, Parameter sizes, MoEs and big copmanies. But this is important. This is the use case that justifies the entire AI revolution, the GPU burns, the buildouts. I want humans to WIN, and Cancer to be fixed!Mayo Clinic just published a study in Gut (BMJ) validating an AI model called REDMOD that detects pancreatic cancer on routine CT scans up to three years before clinical diagnosis. The numbers are jaw-dropping: They show 73% sensitivity for catching prediagnostic cancers, compared to 39% for experienced human radiologists (while looking at the same exact CT scans).And maybe the most important bit, at scans taken more than 2 years before diagnosis, the AI catches nearly 3x as many cases as specialistsFor context: pancreatic cancer has less than 15% five-year survival specifically because 85% of patients are diagnosed after the disease has already spread. This is the cancer that took Steve Jobs. Imagine if Jobs had access to this AI three years before his diagnosis. That’s the impact we’re talking about.As Dr. Ajit Goenka from Mayo Clinic put it, the greatest barrier to saving lives from pancreatic cancer has been the inability to see the disease when it’s still curable. This AI can now identify the signature of cancer from a normal-appearing pancreas.Even better: it runs on CT scans people are already getting for other reasons. No extra screening protocol, no new imaging required. Just smarter analysis of existing data. The model also showed remarkably stable performance across institutions, imaging systems, and protocols, with 90-92% test-retest concordance over serial scans.Mayo Clinic is now moving this into prospective clinical testing through a study called AI-PACED (Artificial Intelligence for Pancreatic Cancer Early Detection).When we say “lets f*****g go” that’s what we mean. Yeah getting more intelligence is cool, but I want a world without decease! Let’s F*****g go mayo clinic! Agentic Commerce - Giving OpenClaw my credit card - safely! Stripe Link Wallet and Infrastructure CLI (X, Announcement, Blog, Announcement)Ok, give an LLM your credit card, what can go wrong.. right? Well, it’s clear that this, increasingly, is the future of commerce. Agents will be shopping for us, and we need solutions here. Well, this week at Stripe Sessions (Stripe’s annual product lineup conference) just delivered. Link Wallet, is a new ... API? CLI? Skill? Definitely a skill, for your agents, to connect with your Stripe Link (the thing that stores your credit cards safely) and then giving your agent a budget, it can go and make purchases in your behalf. Now the trick here, is, every purchase, you get a notification to approve, and the agent never sees y