Cardinals vs. Chargers Week 1 preview, picks, predictions and best bets

The Arizona Cardinals and Los Angeles Chargers play in Week 1. Jess and Seth break down the game, the matchups, the keys to winning, and they make their predictions for the outcome of the game, including some of the best prop bets to make for the game. (1:00) What the Cardinals and Chargers will try to do offensively and defensively (15:46) Keys to victory, matchups to watch (26:18) Picks, predictions and prop bets Follow the show on X: @riseupseered Follow hosts Jess Root (@senorjessroot) and Seth Cox (@SCoxFB) on X as well Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.