The Pulse

The Future of Pain Relief: Managing Chronic Pain, Laughing Gas, and Safer Opioids

July 30, 2026·49 min
Episode Description from the Publisher

Millions of people in the U.S. have chronic pain that’s unresponsive to medical interventions. But there are new and comprehensive ways of treating pain. We explore how emotions, stress, sleep, and diet impact pain, a new option for easing labor pain, and emerging research that could reduce the addictive properties of opioids. We often think of pain as a physical ailment — but newer research shows that pain has as much to do with our brains as it does our bodies. We talk with pain researcher and psychologist Rachel Zoffness about how emotions shape — and construct — our experience of pain, and how identifying the unique biopsychosocial factors contributing to pain can ultimately help patients overcome it. Her new book is "Tell Me Where It Hurts: The New Science of Pain and How to Heal." Giving birth is one of the most painful things many people will experience — which is why a majority of expectant mothers choose epidurals, IV opioids, or both to manage their pain. But recently, another option has been making its way into the delivery room— nitrous oxide, also known as laughing gas. Reporter Andrew Stelzer explains how N02  stacks up against its competitors, and why a growing number hospitals in the U.S. are offering it as an option. Opioids work well on all kinds of pain — but, as the last few decades have shown, they also pose a severe risk of addiction. We talk with neuroscientist and addiction researcher Anjali Rajadhyaksha about a recent discovery that could make opioids safer.

Podzilla Summary coming soon

Sign up to get notified when the full AI-powered summary is ready.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.

Listen to This Episode

Get summaries like this every morning.

Free AI-powered recaps of The Pulse and your other favorite podcasts, delivered to your inbox.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.