#139 - Meet The Greatest Ibogaine Psychedelic Scientist You’ve Never Heard Of

Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giantsGet Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDalibor Sames is the chemist who reverse-engineered ibogaine into a version that appears to erase heroin addiction in a single dose, without the cardiac risk that can kill people on the original drug. He also took his own medicine — and says he watched the molecule's exact 3D structure rotate in front of him for 36 hours straight.Expect to learn why ibogaine breaks every rule of classical pharmacology, what "matrix pharmacology" means and why it's heresy to a one-drug-one-target industry, how editing a single atom deletes ibogaine's fatal heart risk, why a common antidepressant turned out to be a secret opioid for thirty years, what it's like to watch a molecule's structure appear during a 36-hour flood dose, why ibogaine seems to erase interest in alcohol overnight, whether the "DMT block" phenomenon researchers describe is real, and much more…Timestamps0:00:00 Trailer0:02:39 Meet the Chemist Who Fell for a Molecule's Shape0:04:13 The Dogma That the Adult Brain Can't Heal0:09:00 Why Synapses Might Explain Every Brain Disorder0:10:28 Reverse-Engineering Nature's Own Drugs0:16:44 The Paper That Changed Everything About Addiction0:20:01 Why Ibogaine Breaks Every Rule of Pharmacology0:33:08 The Weakest Drug That Works the Strongest0:38:21 The Traffic Jam That Explains Matrix Pharmacology0:44:18 A Human Genome Project — For One Molecule0:47:48 Deciding to Take Ibogaine Himself0:50:02 Inside a 36-Hour Flood Dose0:54:38 The Chapter Called "Treatment"0:56:26 Ibogaine Shows Him the Future of Design1:00:01 Seeing Ibogaine's 3D Molecular Structure1:03:14 High-Fiving a Molecule1:06:47 "This Is a Computational Technology"1:16:36 The Simulation So Real It Panicked Him1:24:26 Did He Earn This Experience?1:30:56 Six Months Later — What Actually Changed1:36:01 Did This Change His View of Consciousness?...... Email for sponsorship enquiries: evan@thegiantsshoulder.comGS Episodes MentionedAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDADavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest LinksColumbia Chemistry faculty page: https://www.chem.columbia.edu/content/dalibor-samesSames Lab: https://www.samesgroup.org/professor-dalibor-samesGilgamesh Pharmaceuticals: https://www.gilgameshpharmaceutical.com/Oxa-Iboga paper (Nature Communications, 2024): https://doi.org/10.1038/s41467-024-51856-yBeond Ibogaine Clinic (where he took ibogaine): https://beondibogaine.com