The Dr. Layne Norton Podcast

AMA 04 - Cortisol, Seed Oils, Insulin, Biggest Loser and More

April 27, 2026·54 min
Episode Description from the Publisher

In this listener Q&A, Layne dives deep into your most-asked questions on training, nutrition, and practical science. As always, he breaks down the actual research and gives no-BS, evidence-based takeaways you can actually use.Topics covered in this episode:• Does cortisol cause fat gain? Plus the impact of low-calorie dieting on cortisol• Sucralose and gut health – new research on dysbiosis, glucose/insulin levels, and the role of Blautia• Do seed oils increase inflammation? Comprehensive look at linoleic acid studies, systematic reviews, and clinical trials• Insulin, high-glycemic carbs, and fat storage – what do overfeeding studies actually show?• Is “natural” always better? The naturalistic fallacy explained• Is resistance training safe and effective for kids? What the science says for youth training• Creatine dosing for women vs. men – do women need a different amount?• Does cardio interfere with building muscle? Latest meta-analyses on concurrent training• Layne’s honest take on The Biggest Loser Netflix documentary• And more!Whether you’re chasing muscle gains, fat loss, or just cutting through the noise, this episode delivers the science-backed answers.SPONSORS• REPS - Research Explained in Practical Summaries: https://biolayne.com/reps• Workout Builder – Customized training programs for all experience levels: https://biolayne.com/workout-builderLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneTIMESTAMPS0:00:00 - Intro0:01:08 - Bulking/Cutting vs Recomp?0:08:00 - Does Cortisol Cause Fat Gain?0:11:51 - REPS Research Review0:12:41 - Does Sucralose Harm Your Gut?0:15:42 - Do Seed Oils Cause Inflammation?0:21:24 - Insulin and Fat Storage?0:25:48 - Workout Builder0:26:43 - Is Natural Always Better?0:31:42 - Can Women Over 60 Grow Their Glutes?0:33:31 - Is Resistance Training Healthy for Kids?0:35:53 - Dosing Creatine for Women vs Men?0:37:00 - Stacy Sims Content?0:40:30 - Alcohol and Body Composition?0:42:45 - Does Cardio Interfere with Building Muscle?0:45:57 - Thoughts on New Biggest Loser Documentary?0:54:04 - OutroSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/

Podzilla Summary coming soon

Sign up to get notified when the full AI-powered summary is ready.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.

Listen to This Episode

Get summaries like this every morning.

Free AI-powered recaps of The Dr. Layne Norton Podcast and your other favorite podcasts, delivered to your inbox.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.