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- Oct 30, 202516 min
AI Meets Bitcoin in Singapore — and Why the U.S. Is Back in the Game with Jesse Darnell
The U.S. crypto scene is finally waking up.After years of regulatory uncertainty and innovation flight, the winds are shifting. Charlie Shrem sits down with Jesse Darnell, former Marine and founder of ADVXNCE Protocol, fresh off Token2049 in Singapore, to talk about why global builders are suddenly turning their eyes back to America.They dive into:What Token2049 reveals about the real direction of crypto in AsiaHow the U.S. is quietly reopening for crypto innovation — from Wyoming to D.C.The rise of “AI + Blockchain” startups and why VCs are finally paying attention againWhat it means to build a company that’s both community-driven and battle-testedLessons from the Marines on leadership, pain, and moving fast in chaosWhy meme coins and serious protocols actually depend on each otherIt’s a grounded, hopeful conversation about where the next wave of building will happen — and what it’ll take to win.Jesse Instagram: https://www.instagram.com/jemappellejesse Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Oct 15, 202519 min
Why Bitcoin’s Biggest Threat- and Opportunity Might- Come from Quantum Physics
“Quantum computing is taking the laws of nature — light, heat, entanglement — and turning them into a new kind of computer. When that happens, the way we think about Bitcoin’s security will have to change forever.” — Charlie ShremThis week on The Charlie Shrem Show, we go deep into the strangest frontier yet: the intersection of Bitcoin, cryptography, and quantum computing.Charlie sits down with Olivier Roussy Newton, OG Bitcoiner and CEO of BTQ Technologies (NASDAQ: BTQ) — a company building at the edge where photons meet blockchains. From his early exposure to D-Wave’s first quantum computers in Canada to raising capital from Chinese state funds (and getting blocked by the CIA’s venture arm), Olivier’s story tracks the entire rise of the post-quantum security industry.Together, Charlie and Olivier unpack what it really means when we say “the end of ECDSA,” why the U.S. government plans to deprecate Bitcoin’s signature standard by 2035, and how quantum systems could make traditional mining obsolete.They explore how the analog world of nature — light, gravity, superconductors — can replace brute-force hashing, how “Boson sampling” could one day stand in for SHA-256, and why the biggest breakthroughs in computing may come from mimicking God’s own architecture.Plus, Charlie shares insights from a recent dinner with Dr. Adam Back and his own stealth research into quantum-mining convergence. This episode isn’t just about crypto’s future — it’s about the future of computation itself.Topics Discussed:From Node.js startups to quantum cryptographyWhat happens when the CIA’s VC fund blocks your dealWhy the U.S. and China’s quantum race matters for BitcoinThe birth of post-quantum cryptography and NIST’s standardsHow quantum encryption could replace proof-of-workWhy consensus itself might become irrelevantHow AI’s mainstream boom paves the way for quantum adoptionThe analog vs. digital computing paradigm shift Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Sep 3, 202526 min
From Surgeon to CEO: Lessons in Frameworks, Funding, and Founders with Nic Roberts-Huntley of Blueprint Finance
What happens when you take the discipline of an Oxford-trained surgeon and apply it to crypto? You get Nic Roberts-Huntley, founder of Concrete and Glow, two of the fastest-growing DeFi protocols.In this episode, Nic and Charlie dive deep into the frameworks, philosophies, and practical decisions that turn ideas into billion-dollar realities. From early mornings at 4:30 AM to late-night calls across continents, Nic’s journey shows how rigor, kindness, and a surgeon’s precision can reshape digital finance.🔑 What You’ll Learn in This EpisodeFrameworks that scale: How lessons from medicine and private equity apply to building DeFi products.Concrete & Glow explained: Institutional-grade yield tools and Solana’s first “margin-first” liquidity engine.Funding playbook: Why the best founders raise on milestones, not desperation.AI + blockchain: Are we building better AI with crypto, or crypto that powers better AI?Team building: The human capital edge — why your first hires define your destiny.Investor relations: Managing Polychain, VanEck, Tribe Capital, and more on your cap table without losing your sanity.Tokenization’s future: From side letters to employee incentives, why tokens are the new equity.Morning routines matter: How Nic structures his 4:30 AM wake-ups, workouts, and workdays to stay sharp.The acquisition story: How Jet Protocol became Glow, and why consolidation is a sign of DeFi’s maturity.🧭 Episode Highlights“**Never raise capital because you need the money. Only raise it because you deserve it.**” — Nic Roberts-HuntleyThe dangers of “vibe coding” in Solidity and how to protect users from liquidation risks.Why DeFi protocols live or die by trust — rugged users rarely return.How Glow is pioneering liquid restaking ($glowSOL) on Solana.The inside story of raising $17M+ and building with backers like Polychain, VanEck, and Portal Ventures.🎙️ About the GuestNic Roberts-Huntley is the founder of Blueprint Finance, the company behind Concrete and Glow. A former Oxford surgeon (MD, MBA) turned Point72 investor, Nic has built a reputation for bridging worlds — from the operating room to private equity to DeFi infrastructure.Concrete: Tokenized DeFi-native asset management and yield optimization on Ethereum (now with $650M+ TVL).Glow: Margin-first liquidity engine and liquid restaking on Solana, acquired from Jet Protocol.🔖 Tags / KeywordsDeFi, Concrete, Glow Finance, Solana, Ethereum, Yield Farming, Tokenization, Restaking, Venture Capital, Polychain, VanEck, Tribe Capital, Crypto Investing, AI + Blockchain, Startups Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Aug 11, 202520 min
The Superfood Biohacker Who’s Helping Crypto Millionaires Fix Their Health with Ian Farrar
In this episode of The Charlie Shrem Show, Charlie sits down with Ian Farrar, a 30-year biohacker, longtime investor, and founding brand partner at Puriam, a direct-to-consumer superfood company. While the crypto space is full of financial innovation, Ian brings the focus back to the most valuable asset you have—your body.They dive deep into what it means to live a "superhuman" lifestyle, how modern diets are failing us, and why wealth without health is a ticking time bomb. Ian shares how green superfoods, gut microbiome balance, and small daily changes can radically transform your life—even if you’re not ready to go full health guru.Topics covered:🥬 Why every Bitcoiner should be thinking about alkalinity and cell charge🍌 How walking barefoot on the beach is better than most supplements📉 Why nutrient density in food has collapsed since the 1970s💊 The harsh truth about Big Pharma vs. lifestyle medicine🧠 How your mindset and gut health are directly connected🛑 Why most alkaline water products are BS (and what actually works)🌍 The case for local food as natural medicine—Colombia vs. the U.S.📱 EMF radiation, cell phones, and protecting your “Faraday bag” body🧪 Full-body scans, thermograms, and futuristic diagnosticsIan also explains the financial literacy parallels between long-term investing and long-term health: both require daily discipline, clarity of purpose, and an understanding of what's coming years down the line.🌿 Mentioned in the episode:Ian’s superfood site: ishopPURIAM.comDiscount code: IAN for $50 off or 25% offIan’s show: Superhuman on Nausik TVBook: Identity Is the New Money by David Birch (also mentioned in Ep. 446)🧘 Bonus:Listeners who use the code “IAN” can also get a free 30-minute lifestyle consultation with Ian. Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Aug 4, 202523 min
Inside Coinbase’s Plan to Make Bitcoin Your Credit Card Rewards with Michael Rihani
In this episode of The Charlie Shrem Show, Charlie is joined by Michael Rihani, Head of Product at Coinbase, to talk about how Bitcoin is finally going mainstream—not just as an investment, but as a spendable, usable financial asset.Michael breaks down the launch of Coinbase’s new American Express-powered credit card, which gives users up to 4% back in Bitcoin on every purchase. Together, they explore what this means for the next generation of crypto adoption and why stablecoins, Lightning payments, and Bitcoin-backed loans are rapidly reshaping the financial stack.Topics covered:🪙 Why the Coinbase Amex card could be crypto’s iPhone moment⚡ The reality of using Bitcoin and Lightning at Steak & Shake📈 $500M in loan originations and the rise of Bitcoin-backed borrowing🌍 How stablecoins are rescuing families from hyperinflation💳 The behind-the-scenes story of working with American Express💡 “Identity is the new money” and the future of frictionless crypto payments🧠 Coinbase's internal X402 project and how it could reinvent internet-native payments🔒 Balancing privacy, identity, and usability in a decentralized futureMichael and Charlie don’t just nerd out on payment protocols—they get real about product-market fit, what crypto users actually want, and how we're moving from trading to real-world utility.📚 Mentioned in the episode:X402 ProtocolIdentity Is the New Money by David BirchCoinbase Credit Card Waitlist: coinbase.com/creditcard Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Jun 13, 202520 min
Bitcoin as Pristine Collateral: Risk Redefined. @PeoplesReserve with @CJKonstantinos
During the darkest days of the last bear market, 5 years ago, I met my friend and guest @CJKonstantinos at The Green Flash in Florida. This guy is the definition of OG by doubling down and starting @peoplesreserve. He's creating Bitcoin-backed financial products that are reshaping the way we think about money.Tomorrow we are both speaking at BitcoinDay Tampa, which always has a way of keeping the culture alive! See you all there!Charlie Highlights:🔒 Bitcoin’s Unmatched Strength: Discover how Bitcoin's undilutable supply creates a truly pristine collateral asset, reshaping loans and financial security.🏡 Never Sell Your Bitcoin for Real Estate Again: CJ shares his unforgettable story of spending 100 Bitcoin on a house—and how @peoplesreserve now helps you secure your dream home without selling your BTC.📊 Smart Adjustable Interest Rates: Learn how adjustable interest rates prevent liquidation and turn Bitcoin volatility into your advantage.🚀 Cross-Collateral Revolution: Understand the groundbreaking combination of Bitcoin and real estate collateral introduced by @peoplesreserve, creating safer financial products.🌐 Redefining the Yield Curve: CJ explains how Bitcoin is creating a new "risk-free" borrower class, challenging traditional finance forever.Why Listen:Explore the future of finance through the lens of Bitcoin-backed mortgages and collateral, directly from one of crypto's boldest innovators. Charlie and CJ unpack how Bitcoin is rapidly becoming the safest, most reliable foundation for wealth preservation and growth.Listen & Subscribe:Subscribe to The Charlie Shrem Show, your twice-weekly source for deep dives with crypto’s most visionary leaders.Guests & Social:CJ Konstantinos → @CJKonstantinosPeople's Reserve → @peoplesreserve Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Jun 6, 202534 min
From Bitcoin to Boat Storage: Joey Rosati on Diversifying Investments
I've gotten to know Joey Rosati (@rosaticorp) over the last 3 years working alonside hime in the VC trenches of Druid Ventures. Let me tell you, the VC world is a funny place and there are gems if you know where to find them. Joey is one of them. He knows that behind every successful business, it's all about people. In today's epic episode, Joey joins me to dive into the "silver tsunami," the massive shift as baby boomers retire, handing off old-school businesses to a younger generation. We talk about buying real-world companies like Dock Builder Supply and Boat Storage, the magic and messiness of mixing traditional business with new tech, and why true success often means blending hustle with humility.Joey shares his own wild entrepreneurial journey—from scratch-off lottery chaos in Guatemala to investing in MLS soccer, and why he now loves "ugly," cash-flowing businesses. We get real about stress, purpose, and why hard money lending might just be the smartest investment out there.We also talk about his role in preserving Tampa's adult entertainment legacy by taking over the world-famous 2001 Odyssey and Mons Venus strip clubs. We explore how he's balancing modernization with tradition, ensuring these establishments continue to thrive in a changing landscape.Buckle up as we cover:The real opportunities behind "boomer businesses."Why software can't replace specialized trades.Managing stress, staying sane, and finding purpose.When (and how) to walk away from a bad deal.Joey's top investment advice for 2025.Connect with Joey on X: @rosaticorp Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
- Apr 23, 202523 min
Bitcoin = Home: The Mortgage Revolution No One Saw Coming with Josip Rupena of Milo
Here’s a sentence I never thought I’d say: you can buy a house with your Bitcoin — without ever selling it.That’s the financial revolution Josip Rupena is building. He’s the founder and CEO of Milo, the fintech startup that’s already issued over $60 million in crypto mortgages — loans backed by your Bitcoin, not your bank account. And here’s the kicker: they’ve never issued a single margin call.In this episode, we break down how it works, what happens behind the scenes, and why this could be one of the most powerful wealth-generating tools in the Bitcoin ecosystem. We also talk about tokenizing mortgages, using AI to streamline lending, and the potential for a future where your Bitcoin unlocks real-world utility — like homes, yield, and financial freedom.This is a rare mix of macro insight, startup strategy, and a deep dive into how crypto is transforming the mortgage game.This episode contains strong language.📚 Mentioned:Milo Crypto Mortgage – www.milo.ioCustodians: Coinbase & BitGoBybit Hack (Largest Hack in History)Tokenized Mortgages & Yield ProductsReal Estate + Bitcoin as a Dual-Asset Lending ModelAI Tools in Underwriting and Client OnboardingUS Housing Inventory Trends (2024–2025)✉️ Feedback or guest ideas?Email Charlie directly and find episodes and transcripts at CharlieShrem.com Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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About The Charlie Shrem Show
Bitcoin pioneer Charlie Shrem peels back the layers on the lives and backgrounds of the world's most impactful innovators. Centering around intimate narratives, Shrem uncovers a detailed, previously unspoken story of the genesis and evolution of bitcoin, cryptocurrency, artificial intelligence, and the web3 movements. Join Shrem as he journeys through the uncharted territories of tech revolutions, revealing the human side of the stories that shaped the digital world we live in today.
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