183 - Hyaluronic Acid – miracle cream or simple moisturizer

Hyaluronic acid is the most versatile ingredient in the beauty industry and promises anti-aging wrinkle-free skin for everyone. Chris and Sophie dive in to find out how much of these claims are based in evidence and whether it does anything beyond moisturizing your skin.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Co-host: Sophie Tseng Pellar Editor:    Robyn Flynn Producer: Danielle Kaprelian   Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris’ book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: 2022 systematic review of topical hyaluronic acid https://pmc.ncbi.nlm.nih.gov/articles/PMC10078143/ A 2025 systematic review and meta-analysis of injectable hyaluronic acid https://pubmed.ncbi.nlm.nih.gov/39807700/ Meta-analysis of 7 randomized controlled trials of oral supplements containing hyaluronic acid https://pubmed.ncbi.nlm.nih.gov/40911749/ Large systematic reviews of skin supplements https://pmc.ncbi.nlm.nih.gov/articles/PMC9201759/ Single large randomized controlled trial of 129 subjects https://pmc.ncbi.nlm.nih.gov/articles/PMC10661223/