Terrain Theory

Redefining Cancer: Toxin Sequestration Theory with Patrick Coles

April 28, 2026·1h 44m
Episode Description from the Publisher

Cancer is typically framed as uncontrolled growth: cells breaking the rules and turning against the body. In this episode, Patrick Coles presents a different theory, one grounded in biophysics and terrain-based thinking, that reframes tumors as part of a larger adaptive process tied to toxic load and metabolic stress. Coles, trained as a physicist, approaches cancer through the lens of systems, thresholds, and testable predictions. His Toxin Sequestration Theory centers on the idea that chron...

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