SYNAPSIS Podcast

#9: The Science of Fasting: Metabolism, Keto Diet, Caloric Restriction, Intermittent Fasting, and Ramadan Fasting

March 7, 2025·27 min
Episode Description from the Publisher

Is fasting really healthy? How do caloric restriction and intermittent fasting affect our brain and body? What are the differences between Ramadan fasting and other types of fasting?In this video, I explore the science of fasting, its effects on metabolism, its connection to the keto diet, and how prolonged fasting changes the body at a cellular level. Covering all the studies in one episode is unfortunately impossible, so feel free to ask any additional questions in the comments on YouTube or Instagram @synapsispodcast!Some of the questions I try to answer:✔️ What happens in the body during fasting?✔️ Does caloric restriction really extend lifespan?✔️ What is the relationship between fasting and ketosis?✔️ How does fasting affect the brain?✔️ What is the healthiest way to break a fast?Timestamps:00:00 - 02:30 Introduction02:30 - 03:50 Metabolism: Fasting vs. Fed State03:50 - 06:00 Glucose, Insulin, and Diabetes06:00 - 07:30 Glucose Storage and Transition to Fat Burning07:30 - 10:00 Types of Fasting10:00 - 13:00 Glucose in the Brain, Brain Injuries, and Epilepsy13:00 - 16:35 Brain Health, Keto Diet & Fasting, Alzheimer's16:20 - 21:00 Cardiovascular/Metabolic/Systemic Effects21:00 - 24:00 Ideal Meals for Breaking a Fast24:00 - 26:00 Summary & Conclusion

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