RP Strength Podcast

Why Some People Build Muscle Slower: Are "Non-Responders" Real? | Dr. Eric Trexler

August 3, 2026·55 min
Episode Description from the Publisher

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Guest Links Dr. Eric Trexler's Links: Instagram: @trexlerfitness ResearchGate: Eric Trexler publications Research review: MASS Research Review Timestamps 00:00 Conference travel, weight-loss non-responders, and the episode setup 07:03 What counts as a training non-responder? 08:53 Measurement error and why short studies can mislead 10:53 Replication and better individualized research designs 16:30 General response versus program-specific response 19:25 Why advanced lifters struggle to measure small changes 33:34 Can muscle fiber type affect training responsiveness? 37:22 Why narrower studies produce better answers 39:28 Are true non-responders real? 44:10 What to do when your progress is unusually slow 50:27 Before you give up: time, volume, intensity, and mindset 54:39 The calf-training example, Eric's links, and closing

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