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Psychopharmacology and Psychiatry Updates

Clozapine Monitoring: New Guidelines for the Post-REMS Era

May 1, 2026·12 min
Episode Description from the Publisher

In this episode, we explore new international guidelines for clozapine monitoring following the FDA's REMS rescission. Should patients on stable clozapine continue lifelong monthly blood draws, or can we safely reduce monitoring after two years? Dr. Seeber discusses how these evidence-based recommendations balance patient burden with safety. Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 79 New Guidelines for Clozapine ANC Monitoring

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