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Helping the industry understand how it will revolutionize modern protein production and help build a healthier, more efficient, and sustainable global protein system
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Powered by Protein Production Technology InternationalA breakthrough ingredient or production process may create headlines, but can it create a defensible business?In this episode of the Protein Production Technology International podcast, Nick Bradley was joined by Kerry Rees and Andrew Tindall of HGF, alongside Gilbert Verschelling of The Protein Brewery, Tim Fronzek of Nosh.bio, and Casey Lippmeier of Checkerspot, to explore how alternative protein companies can build intellectual property strategies that support long-term commercial success.The panel discussed why effective IP management extends far beyond filing patents, examining how founders can align protection strategies with business objectives, fundraising plans, partnerships, and commercialization roadmaps. The conversation explored the balance between patents and trade secrets, the risks of over-filing, and how companies can ensure their most valuable innovations remain protected as they scale.The speakers also shared insights into what investors look for when assessing technology businesses, explaining why strong IP portfolios can strengthen a company's position but are rarely enough on their own. Market traction, execution capability, regulatory progress, and commercial readiness all play critical roles in building investor confidence.From collaboration agreements and freedom-to-operate considerations to licensing strategies and enforcement, the discussion offered practical guidance for founders navigating one of the most important - and often misunderstood - aspects of building an alternative protein company.A must-listen for founders, R&D leaders, investors, legal teams, and anyone seeking to transform innovation into a scalable and defensible business.
Powered by Protein Production Technology InternationalWhat does it take for a biotechnology company to evolve from a promising startup into a commercially focused nutrition business?In this episode of the Protein Production Technology International podcast, Nick Bradley sat down with John Krzywicki, CEO of Checkerspot, to discuss the company's journey from developing industrial materials to commercializing high-value nutritional ingredients derived from microalgae.Krzywicki shared how Checkerspot is using heterotrophic microalgae and precision fermentation to produce specialty fats and oils, including ingredients designed to replicate those found naturally in human breast milk. The conversation explored why microalgae offers unique advantages as a production platform and how advances in biotechnology are opening new opportunities in infant nutrition and broader health applications.The discussion also provided a candid look at the realities of scale-up, including resource allocation, capital efficiency, and the strategic decisions required to focus on the most commercially attractive opportunities. Krzywicki explained why partnerships have played a critical role in the company's growth and how Checkerspot's licensing-led approach is designed to accelerate adoption while minimizing capital requirements.From ingredient innovation and commercialization to manufacturing strategy and market focus, the episode highlighted the challenges and opportunities facing biotechnology companies as they transition from technology development to sustainable business growth.A must-listen for fermentation companies, ingredient developers, nutrition brands, investors, and anyone interested in the commercialization of next-generation food ingredients.
Powered by Protein Production Technology InternationalWhy do so many promising biotechnology breakthroughs fail to reach commercial scale?In this episode of the Protein Production Technology International podcast, Nick Bradley sat down with Thomas G. Schmidt, CEO of 21st.BIO, to discuss one of the industry's biggest challenges: bridging the 'Valley of Death' between laboratory success and industrial-scale production.Drawing on the company's roots within the Novo Group ecosystem, Schmidt explained how 21st.BIO is helping startups accelerate commercialization by providing access to proven technology platforms, industrial expertise, and large-scale production capabilities. The conversation explored why scientific innovation alone is rarely enough and why companies must demonstrate credible pathways to manufacturing at scale.Schmidt also shared his perspective on the future economics of precision fermentation, including why achieving competitive production costs, improving titers, and maximizing carbon conversion efficiency will be critical to long-term success. The discussion examined 21st.BIO's work with beta-lactoglobulin (BLG), the importance of moving beyond sustainability-focused narratives, and the need to build businesses that can compete on performance and economics.The episode also looked at how biotechnology can evolve from replicating existing proteins to creating entirely new nutritional possibilities, unlocking greater efficiency and helping meet growing global demand for protein.From scale-up and manufacturing to investment, partnerships, and the future of precision fermentation, this conversation offered valuable insights into what it will take to transform breakthrough science into commercially viable food production.A must-listen for fermentation companies, investors, food manufacturers, technology developers, and anyone interested in the realities of scaling the next generation of protein production.
Powered by Protein Production Technology InternationalCan dairy proteins be produced without cows while still delivering the taste, texture, and functionality consumers expect?In this episode of the Protein Production Technology International podcast, Nick Bradley sat down with Yvan Chardonnens, CEO of Standing Ovation, to discuss how precision fermentation is being used to produce animal-free casein and what that could mean for the future of dairy.Chardonnens explained why casein remains one of the most challenging and important dairy proteins to replicate, particularly for applications such as cheese, where melt, stretch, and texture are critical. The conversation explored Standing Ovation's approach to producing casein through fermentation, as well as the company's broader ambition to help address growing global protein demand.A key focus of the discussion was Standing Ovation's circular economy model, which utilizes dairy industry side streams such as acid whey as fermentation feedstocks. Chardonnens shared how this approach can reduce production costs while creating new value streams for dairy processors, demonstrating how traditional and emerging food technologies can work together.The episode also examined partnerships with major dairy companies, progress toward regulatory approval in the USA, and the potential role of hybrid dairy products in introducing fermentation-derived proteins to consumers.From food sovereignty and sustainability to commercialization and consumer acceptance, this conversation offered a detailed look at how precision fermentation could help reshape the future of dairy production.A must-listen for dairy companies, food manufacturers, fermentation innovators, investors, and anyone interested in the next generation of functional proteins.
Powered by Protein Production Technology InternationalWhat if cultivated meat's first commercial breakthrough comes through pet food rather than human food?In this episode of the Protein Production Technology International podcast, Nick Bradley sat down with Joshua Errett, Founder and CEO of Friends & Family Pet Food Company, to discuss the launch of cultivated pet food in Singapore and why he believes the category could become one of the most important early markets for cultivated proteins.Drawing on more than a decade in the alternative protein sector, Errett shared his perspective on the industry's evolution and explained why he views cultivated meat as an entirely new ingredient platform rather than simply an alternative to conventional meat. The conversation explored changing consumer expectations around pet nutrition, the growing shift away from highly processed kibble, and the opportunity to deliver fresher, higher-quality ingredients for companion animals.Errett also discussed the limitations of traditional rendering processes, the importance of preserving protein quality and essential amino acids, and why communicating clear nutritional benefits matters more than focusing on the technical details behind production.From commercialization and consumer acceptance to sustainability and animal health, the discussion offered a fascinating look at how cultivated proteins could reshape one of the world's largest and fastest-growing pet food markets.A must-listen for pet food manufacturers, cultivated meat companies, investors, and anyone interested in where alternative proteins may achieve their next major commercial milestone.
Powered by Protein Production Technology InternationalHow do you tell the story of an industry that is constantly reinventing itself?In this episode of the Protein Production Technology International podcast, Nick Bradley sat down with Alex Crisp, founder and host of the Future Foods Podcast, to discuss the evolution of alternative protein storytelling and the role media plays in shaping public understanding of food innovation.Drawing on an unconventional background spanning law, teaching, and amateur dramatics, Crisp reflected on his journey from curious industry newcomer to one of the sector's most recognizable podcast hosts. The conversation explored how alternative protein narratives have matured, why transparency and authenticity matter more than ever, and how communicators can bridge the gap between complex science and mainstream audiences.The discussion also examined the industry's expanding focus beyond cultivated meat, including growing interest in mycelium, fermentation, and broader sustainable food solutions. Throughout the episode, Crisp shared his perspective on building trust, avoiding hype, and creating meaningful conversations that resonate with both industry insiders and the wider public.A must-listen for founders, researchers, communicators, investors, and anyone interested in how the future of food is being explained, debated, and understood.
Powered by Protein Production Technology InternationalWhat happens when alternative protein developers stop asking whether products should be plant-based or meat-based and start combining the best of both worlds?In this episode of the Protein Production Technology International podcast, Caroline Cotto of NECTAR, Mylène Potier of Gira, Marc Renauld of Roquette, and Marion Lefebvre of Roquette explored why hybrid meat is emerging as one of the most commercially compelling opportunities in food innovation.The discussion examined how combining complementary protein sources can help overcome some of the industry's biggest formulation challenges, including taste, texture, structure, nutrition, and affordability. The panel also shared insights into how hybrid approaches can improve product performance while helping manufacturers navigate cost pressures and scale production more effectively.From ingredient functionality and consumer acceptance to real-world product development strategies, the conversation highlighted why hybrid meat is increasingly being viewed not as a compromise, but as a practical route to bringing better products to market.A must-listen for product developers, ingredient suppliers, food manufacturers, retailers, and anyone interested in the next phase of alternative protein innovation.
Powered by Protein Production Technology InternationalBuilding a successful fermentation company is one thing. Financing a commercial-scale facility is another entirely.In this episode of the Protein Production Technology International podcast, Diana Rucinschi of the European Innovation Fund, David Ziskind of Mach Global Advisors, Aakriti Mehta of Channel Capital Advisors, and Spencer White of Unibio joined host Nick Bradley to tackle one of the industry's biggest challenges: bridging the capital gap between pilot success and industrial deployment.The panel explored why venture capital alone cannot fund the next generation of fermentation infrastructure, what lenders and project financiers need to see before committing capital, and how companies can combine equity, debt, strategic partnerships, offtake agreements, and public-private funding to unlock growth.From becoming genuinely 'finance-ready' to reducing risk for investors and infrastructure partners, the discussion offered a practical look at how fermentation companies can move beyond promising technology and into commercial-scale manufacturing.A must-listen for founders, investors, CFOs, and anyone involved in scaling fermentation from demonstration to industrial reality.
Helping the industry understand how it will revolutionize modern protein production and help build a healthier, more efficient, and sustainable global protein system
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