Physiological Reviews Podcast

Impact of Vaping on the Immune System

April 1, 2026·38 min
Episode Description from the Publisher

In this episode Editor-in-Chief Dr. Sadis Matalon (University of Alabama Birmingham) interviews author Dr. Laura Crotty Alexander (University of California, San Diego) about the recently published Review article by Masso-Silva et al. on the impact of e-cigarette vaping on the immune system across the body. We discuss in depth how vaping limits the ability of alveolar macrophages to protect the body from pathogens, and cover the impact of vaping on T cells, the powerhouse cells of adaptive immunity, to respond robustly to tumor antigens. Does vaping impact the rate of tumor growth in cancer patients, particularly breast cancer and prostate cancer? Listen now to learn much more.   Jorge A. Masso-Silva, Alexia Perryman, Sophia Karandashova, Avnee Jaya Kumar, Laura Barnes, Nikita Kasaraneni, and Laura E. Crotty Alexander Impact of e-cigarette vaping on the immune system across the body Physiological Reviews, published January 24, 2026. DOI: 10.1152/physrev.00011.2025

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