Episode 330 - Marcelo Marucho, PhD

On April 9, 2026 I spoke with Dr. Marcelo Marucho, on the electrical properties of actin filaments and microtubules, ubiquitous components of the cytoskeleton of nearly all cells. He explained how the surface charge of these proteins creates a thin charged layer in the adjacent cytoplasm in which electrical signals may be generated and conducted. In the case of microtubules, the interaction between external and luminal surfaces can produce oscillations. We discussed some of the possible functions of these electrical signals in the brain.Guest:Marcelo Marucho, Professor, Department of Physics and Astronomy, UTSAHost:Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA