NEJM AI Grand Rounds

Epic’s Approach to AI with Seth Hain

February 18, 2026·53 min
Episode Description from the Publisher

Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain describes how Epic is building foundation models that respect institutional autonomy, minimize burden, and prioritize safety. He discusses scaling laws in structured medical data, cautious deployment for clinical interventions, and why understanding causality—not just correlation—is essential. This conversation reframes AI not as disruption, but as infrastructure for safer, more reliable care. Transcript.

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