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My Favorite Learners Podcast

Antihypertensives & Anesthesia: The Meds That Love to Mess with Your Hemodynamics with Chloe Gomez, DNP, CRNA

December 29, 2025·28 min
Episode Description from the Publisher

Antihypertensive medications don’t have to feel overwhelming or memorization-heavy. In this solo lecture, Chloe Gomez, DNP, CRNA breaks down antihypertensive pharmacology through physiology, mechanisms of action, and real-world anesthesia implications - exactly what SRNAs, CRNAs, and anesthesia providers need for boards and the operating room.This episode walks through the major classes of antihypertensives, focusing on how each drug lowers blood pressure rather than relying on disconnected lists. You’ll learn how antihypertensives interact with preload, afterload, heart rate, contractility, and systemic vascular resistance, and why those effects matter during induction, maintenance, and emergence from anesthesia.Key topics covered include:Beta blockers (β₁ vs β₂ effects, perioperative continuation, blunted sympathetic response)ACE inhibitors (ACE-Is) & ARBs: RAAS physiology, vasodilation, and refractory hypotensionCalcium channel blockers (DHP vs non-DHP): vascular vs nodal effectsAlpha agonists and antagonistsHow antihypertensives alter MAP, CO, SVR, and reflex tachycardiaWhy certain antihypertensives increase the risk of induction hypotensionWhat to hold, continue, or anticipate on the day of surgeryThroughout the episode, complex pharmacology is tied directly to:Hemodynamic management in anesthesiaCommon board scenarios and NBCRNA-style reasoningVasopressor choice and responseDrug interactions with propofol, volatile agents, opioids, and neuraxial anesthesiaThis lecture emphasizes understanding over memorization, helping anesthesia learners build a framework they can use in high-stakes clinical moments - not just exam day.🎧 Antihypertensives explained for anesthesia learners - fewer flashcards, more confidence, safer patients.

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