Mayo Clinic on Nutrition

Understanding Obesity Phenotypes

April 21, 2026·37 min
Episode Description from the Publisher

Why do some people seem to shed weight easily while others don’t get the same results, no matter how hard they try? According to the theory of obesity phenotypes, the way each of us gains weight is different — and the best way to lose it may be different, too. On this episode of On Nutrition, bariatrician, gastroenterologist and internist Dr. Andres Acosta shares his research on obesity phenotypes, how genetics can play a role in developing obesity, and how a person’s phenotype gives providers a pathway to tailor treatment. Sign up⁠ to receive Mayo Clinic Press emails.  Find us online at ⁠Mayo Clinic Press⁠ for more health and wellness articles, podcasts and books.  Do you have feedback, questions or topic suggestions? Email us at ⁠mcppodcasts@mayo.edu⁠.

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