Longevity Optimization with Kayla Barnes-Lentz

GLP-1 Crisis for Women, Gut Health, Bone Loss with Dr. Sara Szal, MD

April 16, 2026·1h 13m
Episode Description from the Publisher

We're back with Dr. Szal! Today we are discussing a variety of topics: Gut health, peptides, hormone health , GLP-1's, bone health and so much more!In this conversation, Dr. Sara G dives into the gut-brain connection and explains how disrupting the microbiome can directly affect mood, anxiety, and overall mental resilience. She breaks down why even a single course of antibiotics can shift the balance of your gut in ways most people never consider, and what that means for how you feel day to day.This is where the gut-brain connection becomes practical, not theoretical. Instead of treating symptoms in isolation, understanding how the microbiome regulates neurotransmitters and inflammation changes the way these issues are approached.Rebuilding that system requires more than random probiotics or diet changes. The Weed, Seed, Feed framework focuses on restoring gut balance in the right order, removing what doesn’t belong, reintroducing beneficial bacteria, and supporting their growth long-term.This episode is sponsored by Zen Basil. Their certified edible basil seeds are designed for human nutrition, deliver 15g of fiber per serving, and are batch-tested for glyphosate and over 400 pesticides. Use code KAYLA20 for 20% off.https://zenbasil.com/shopzenbasil/zenbasilseedbagJoin the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/female-longevity-communityIn this conversation:-Antibiotics and anxiety (25–50% increase)-The gut-brain connection explained simply-What happens when the microbiome is disrupted-Why most gut protocols don’t work-Weed, Seed, Feed framework-How to rebuild gut health properlyConnect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.comLearn more about Dr. Sara:Instagram: https://www.instagram.com/saragottfriedmd/Website: https://saraszalmd.com/YouTube: www.youtube.com/@SaraSzalMDFollow her on Substack:https://saraszalmd.substack.com/

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