Born to Live Longer? Inside the Genetics and Biology of Centenarians

In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Paola Sebastiani, Professor of Biostatistics at Tufts Clinical and Translational Science Institute. They explore what centenarians reveal about reaching 100, and why there’s no single longevity gene. Paola explains that studies keep finding many small genetic effects, which makes polygenic risk scores hard to use for personal prediction. She says progress depends on bigger cohorts and new analyses that include st...